World Marrow Donor Association guidelines for the reporting of novel HLA alleles

Jan A Hofmann; Werner Bochtler; James Robinson; Jürgen Sauter; Medhat Askar; Lucie Houdova; Mark Melchers; Alexander H Schmidt; Eric Spierings; Christine Urban; Alicia Venter; Martin Maiers; Steven G E Marsh; Hans-Peter Eberhard

doi:10.1111/tan.15048

World Marrow Donor Association guidelines for the reporting of novel HLA alleles

Jan A Hofmann, Werner Bochtler, James Robinson, Jürgen Sauter, Medhat Askar, Lucie Houdova, Mark Melchers, Alexander H Schmidt, Eric Spierings, Christine Urban, Alicia Venter, Martin Maiers, Steven G E Marsh, Hans-Peter Eberhard

Research output: Contribution to journal › Article › Academic › peer-review

21 Downloads (Pure)

Abstract

The guidelines for the implementation and reporting of HLA nomenclature for the World Marrow Donor Association have served as a reliable standard for communication of HLA data in the hematopoietic cell transplantation process. Wider use of next-generation sequencing made a special provision of the guidelines increasingly pertinent: how to communicate novel HLA alleles. Novel alleles need to be recognized by the WHO Nomenclature Committee for Factors of the HLA system to obtain official allele designations. Until then they have to be handled according to the specific rules. Leaving the actual rules basically unchanged we give some advice on how to communicate novel alleles to best facilitate the search process for cases where novel alleles are identified on donor or patient side.

Original language	English
Pages (from-to)	62-64
Number of pages	3
Journal	HLA
Volume	102
Issue number	1
Early online date	10 Apr 2023
DOIs	https://doi.org/10.1111/tan.15048
Publication status	Published - Jul 2023

Keywords

donor registry
HLA
new alleles
NGS typing
patient registry

Access to Document

10.1111/tan.15048Licence: CC BY-NC-ND

HLA - 2023 - Hofmann - World Marrow Donor Association guidelines for the reporting of novel HLA allelesFinal published version, 933 KBLicence: CC BY-NC-ND

Cite this

@article{a17f46bee5b2408ab492795a583046dd,

title = "World Marrow Donor Association guidelines for the reporting of novel HLA alleles",

abstract = "The guidelines for the implementation and reporting of HLA nomenclature for the World Marrow Donor Association have served as a reliable standard for communication of HLA data in the hematopoietic cell transplantation process. Wider use of next-generation sequencing made a special provision of the guidelines increasingly pertinent: how to communicate novel HLA alleles. Novel alleles need to be recognized by the WHO Nomenclature Committee for Factors of the HLA system to obtain official allele designations. Until then they have to be handled according to the specific rules. Leaving the actual rules basically unchanged we give some advice on how to communicate novel alleles to best facilitate the search process for cases where novel alleles are identified on donor or patient side.",

keywords = "donor registry, HLA, new alleles, NGS typing, patient registry",

author = "Hofmann, {Jan A} and Werner Bochtler and James Robinson and J{\"u}rgen Sauter and Medhat Askar and Lucie Houdova and Mark Melchers and Schmidt, {Alexander H} and Eric Spierings and Christine Urban and Alicia Venter and Martin Maiers and Marsh, {Steven G E} and Hans-Peter Eberhard",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors. HLA: Immune Response Genetics published by John Wiley & Sons Ltd.",

year = "2023",

month = jul,

doi = "10.1111/tan.15048",

language = "English",

volume = "102",

pages = "62--64",

number = "1",

}

TY - JOUR

T1 - World Marrow Donor Association guidelines for the reporting of novel HLA alleles

AU - Hofmann, Jan A

AU - Bochtler, Werner

AU - Robinson, James

AU - Sauter, Jürgen

AU - Askar, Medhat

AU - Houdova, Lucie

AU - Melchers, Mark

AU - Schmidt, Alexander H

AU - Spierings, Eric

AU - Urban, Christine

AU - Venter, Alicia

AU - Maiers, Martin

AU - Marsh, Steven G E

AU - Eberhard, Hans-Peter

PY - 2023/7

Y1 - 2023/7

N2 - The guidelines for the implementation and reporting of HLA nomenclature for the World Marrow Donor Association have served as a reliable standard for communication of HLA data in the hematopoietic cell transplantation process. Wider use of next-generation sequencing made a special provision of the guidelines increasingly pertinent: how to communicate novel HLA alleles. Novel alleles need to be recognized by the WHO Nomenclature Committee for Factors of the HLA system to obtain official allele designations. Until then they have to be handled according to the specific rules. Leaving the actual rules basically unchanged we give some advice on how to communicate novel alleles to best facilitate the search process for cases where novel alleles are identified on donor or patient side.

AB - The guidelines for the implementation and reporting of HLA nomenclature for the World Marrow Donor Association have served as a reliable standard for communication of HLA data in the hematopoietic cell transplantation process. Wider use of next-generation sequencing made a special provision of the guidelines increasingly pertinent: how to communicate novel HLA alleles. Novel alleles need to be recognized by the WHO Nomenclature Committee for Factors of the HLA system to obtain official allele designations. Until then they have to be handled according to the specific rules. Leaving the actual rules basically unchanged we give some advice on how to communicate novel alleles to best facilitate the search process for cases where novel alleles are identified on donor or patient side.

KW - donor registry

KW - HLA

KW - new alleles

KW - NGS typing

KW - patient registry

UR - http://www.scopus.com/inward/record.url?scp=85152459181&partnerID=8YFLogxK

U2 - 10.1111/tan.15048

DO - 10.1111/tan.15048

M3 - Article

C2 - 37038092

SN - 2059-2302

VL - 102

SP - 62

EP - 64

JO - HLA

JF - HLA

IS - 1

ER -

World Marrow Donor Association guidelines for the reporting of novel HLA alleles

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this