When observational studies are as helpful as randomized trials: Examples from orthopedic trauma: Examples from orthopedic trauma

R B Beks; Abhiram R Bhashyam; R M Houwert; D van der Velde; M van Heijl; Dpj Smeeing; F Hietbrink; L P H Leenen; Rhh Groenwold

doi:10.1097/TA.0000000000002347

When observational studies are as helpful as randomized trials: Examples from orthopedic trauma: Examples from orthopedic trauma

R B Beks
, Abhiram R Bhashyam
, R M Houwert
, D van der Velde
, M van Heijl
, Dpj Smeeing
, F Hietbrink
, L P H Leenen
, Rhh Groenwold

Research output: Contribution to journal › Review article › peer-review

1 Downloads (Pure)

Abstract

Randomized controlled trials (RCTs) are often challenging to design in surgical fields and can be misleading when poorly executed. While the prevailing belief is that observational studies on therapeutic efficacy are credible only in exceptional circumstances due to unrecognized confounding, we identify three types of intervention in orthopaedic trauma and illustrate relevant features that allow observational studies in orthopaedic surgery to be as helpful as RCTs.

Original language	English
Pages (from-to)	730-732
Number of pages	3
Journal	The Journal of Trauma and Acute Care Surgery
Volume	87
Issue number	3
Early online date	25 Apr 2019
DOIs	https://doi.org/10.1097/TA.0000000000002347
Publication status	Published - Sept 2019

Keywords

Bone and Bones/injuries
Humans
Observational Studies as Topic
Orthopedic Procedures
Randomized Controlled Trials as Topic

Access to Document

10.1097/TA.0000000000002347

When_observational_studies_are_as_helpful_as.33Final published version, 120 KBLicence: Taverne

Cite this

Beks, R. B., Bhashyam, A. R., Houwert, R. M., van der Velde, D., van Heijl, M., Smeeing, D., Hietbrink, F., Leenen, L. P. H., & Groenwold, R. (2019). When observational studies are as helpful as randomized trials: Examples from orthopedic trauma: Examples from orthopedic trauma. The Journal of Trauma and Acute Care Surgery, 87(3), 730-732. https://doi.org/10.1097/TA.0000000000002347

@article{fb30be63887142258c8c89d1a4b7a4f5,

title = "When observational studies are as helpful as randomized trials: Examples from orthopedic trauma: Examples from orthopedic trauma",

abstract = "Randomized controlled trials (RCTs) are often challenging to design in surgical fields and can be misleading when poorly executed. While the prevailing belief is that observational studies on therapeutic efficacy are credible only in exceptional circumstances due to unrecognized confounding, we identify three types of intervention in orthopaedic trauma and illustrate relevant features that allow observational studies in orthopaedic surgery to be as helpful as RCTs.",

keywords = "Bone and Bones/injuries, Humans, Observational Studies as Topic, Orthopedic Procedures, Randomized Controlled Trials as Topic",

author = "Beks, \{R B\} and Bhashyam, \{Abhiram R\} and Houwert, \{R M\} and \{van der Velde\}, D and \{van Heijl\}, M and Dpj Smeeing and F Hietbrink and Leenen, \{L P H\} and Rhh Groenwold",

year = "2019",

month = sep,

doi = "10.1097/TA.0000000000002347",

language = "English",

volume = "87",

pages = "730--732",

journal = "The Journal of Trauma and Acute Care Surgery",

issn = "2163-0755",

publisher = "Lippincott Williams \& Wilkins",

number = "3",

}

Beks, RB, Bhashyam, AR, Houwert, RM, van der Velde, D, van Heijl, M, Smeeing, D, Hietbrink, F, Leenen, LPH & Groenwold, R 2019, 'When observational studies are as helpful as randomized trials: Examples from orthopedic trauma: Examples from orthopedic trauma', The Journal of Trauma and Acute Care Surgery, vol. 87, no. 3, pp. 730-732. https://doi.org/10.1097/TA.0000000000002347

TY - JOUR

T1 - When observational studies are as helpful as randomized trials: Examples from orthopedic trauma

T2 - Examples from orthopedic trauma

AU - Beks, R B

AU - Bhashyam, Abhiram R

AU - Houwert, R M

AU - van der Velde, D

AU - van Heijl, M

AU - Smeeing, Dpj

AU - Hietbrink, F

AU - Leenen, L P H

AU - Groenwold, Rhh

PY - 2019/9

Y1 - 2019/9

N2 - Randomized controlled trials (RCTs) are often challenging to design in surgical fields and can be misleading when poorly executed. While the prevailing belief is that observational studies on therapeutic efficacy are credible only in exceptional circumstances due to unrecognized confounding, we identify three types of intervention in orthopaedic trauma and illustrate relevant features that allow observational studies in orthopaedic surgery to be as helpful as RCTs.

AB - Randomized controlled trials (RCTs) are often challenging to design in surgical fields and can be misleading when poorly executed. While the prevailing belief is that observational studies on therapeutic efficacy are credible only in exceptional circumstances due to unrecognized confounding, we identify three types of intervention in orthopaedic trauma and illustrate relevant features that allow observational studies in orthopaedic surgery to be as helpful as RCTs.

KW - Bone and Bones/injuries

KW - Humans

KW - Observational Studies as Topic

KW - Orthopedic Procedures

KW - Randomized Controlled Trials as Topic

UR - https://www.scopus.com/pages/publications/85071710554

U2 - 10.1097/TA.0000000000002347

DO - 10.1097/TA.0000000000002347

M3 - Review article

C2 - 31045741

SN - 2163-0755

VL - 87

SP - 730

EP - 732

JO - The Journal of Trauma and Acute Care Surgery

JF - The Journal of Trauma and Acute Care Surgery

IS - 3

ER -

When observational studies are as helpful as randomized trials: Examples from orthopedic trauma: Examples from orthopedic trauma

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this