TY - JOUR
T1 - What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure
AU - Amelotti, Nicola
AU - Mapelli, Massimo
AU - Guglielmo, Marco
AU - Pires, Maria Inês Fiuza Branco
AU - Campodonico, Jeness
AU - Majocchi, Benedetta
AU - Ribatti, Valentina
AU - Vettor, Giulia
AU - Baggiano, Andrea
AU - Catto, Valentina
AU - Basso, Cristina
AU - Pontone, Gianluca
AU - Agostoni, Piergiuseppe
N1 - Publisher Copyright:
© 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.
PY - 2023/2
Y1 - 2023/2
N2 - Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67-year-old woman presented with 1-week history of dyspnoea and orthopnoea. She had a history of adult-onset asthma and peripheral eosinophilia. The investigations showed T-wave inversion on lateral leads, peripheral eosinophilia, elevated troponin and BNP values, and severe biventricular systolic dysfunction with diffuse hypokinesia and apical akinesia. Computed tomography excluded coronary disease and showed bilateral basal ground-glass opacities, air-space consolidation, and bilateral reticular-nodular pattern. Cardiac magnetic resonance findings were compatible with active myocardial inflammation. An endomyocardial biopsy (EMB) confirmed the diagnosis of eosinophilic myocarditis, and a therapy with oral corticosteroids and heart failure medications was started.
AB - Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67-year-old woman presented with 1-week history of dyspnoea and orthopnoea. She had a history of adult-onset asthma and peripheral eosinophilia. The investigations showed T-wave inversion on lateral leads, peripheral eosinophilia, elevated troponin and BNP values, and severe biventricular systolic dysfunction with diffuse hypokinesia and apical akinesia. Computed tomography excluded coronary disease and showed bilateral basal ground-glass opacities, air-space consolidation, and bilateral reticular-nodular pattern. Cardiac magnetic resonance findings were compatible with active myocardial inflammation. An endomyocardial biopsy (EMB) confirmed the diagnosis of eosinophilic myocarditis, and a therapy with oral corticosteroids and heart failure medications was started.
KW - Cardiac magnetic resonance
KW - Endomyocardial biopsy
KW - Eosinophilic granulomatosis with polyangiitis (Churg–Strauss)
KW - Eosinophilic myocarditis
KW - Heart failure
UR - http://www.scopus.com/inward/record.url?scp=85140021086&partnerID=8YFLogxK
U2 - 10.1002/ehf2.14172
DO - 10.1002/ehf2.14172
M3 - Article
C2 - 36259268
AN - SCOPUS:85140021086
SN - 2055-5822
VL - 10
SP - 709
EP - 715
JO - ESC heart failure
JF - ESC heart failure
IS - 1
ER -