VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface.

P.D. Eckford; M. Ramjeesingh; S. Molinski; S. Pasyk; J.F. Dekkers; C. Li; S. Ahmadi; W. Ip; T.E. Chung; K. Du; H. Yeger; J.M. Beekman; T. Gonska; C.E. Bear

doi:10.1016/j.chembiol.2014.02.021

VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface.

P.D. Eckford, M. Ramjeesingh, S. Molinski, S. Pasyk, J.F. Dekkers, C. Li, S. Ahmadi, W. Ip, T.E. Chung, K. Du, H. Yeger, J.M. Beekman, T. Gonska, C.E. Bear

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	666-678
Number of pages	13
Journal	Chemistry & Biology
Volume	21
Issue number	5
DOIs	https://doi.org/10.1016/j.chembiol.2014.02.021
Publication status	Published - 2014

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10.1016/j.chembiol.2014.02.021

http://www.sciencedirect.com/science/article/pii/S1074552114001082

Cite this

Eckford, P. D., Ramjeesingh, M., Molinski, S., Pasyk, S., Dekkers, J. F., Li, C., Ahmadi, S., Ip, W., Chung, T. E., Du, K., Yeger, H., Beekman, J. M., Gonska, T., & Bear, C. E. (2014). VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface. Chemistry & Biology, 21(5), 666-678. https://doi.org/10.1016/j.chembiol.2014.02.021

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title = "VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface.",

author = "P.D. Eckford and M. Ramjeesingh and S. Molinski and S. Pasyk and J.F. Dekkers and C. Li and S. Ahmadi and W. Ip and T.E. Chung and K. Du and H. Yeger and J.M. Beekman and T. Gonska and C.E. Bear",

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Eckford, PD, Ramjeesingh, M, Molinski, S, Pasyk, S, Dekkers, JF, Li, C, Ahmadi, S, Ip, W, Chung, TE, Du, K, Yeger, H, Beekman, JM, Gonska, T & Bear, CE 2014, 'VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface.', Chemistry & Biology, vol. 21, no. 5, pp. 666-678. https://doi.org/10.1016/j.chembiol.2014.02.021

TY - JOUR

T1 - VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface.

AU - Eckford, P.D.

AU - Ramjeesingh, M.

AU - Molinski, S.

AU - Pasyk, S.

AU - Dekkers, J.F.

AU - Li, C.

AU - Ahmadi, S.

AU - Ip, W.

AU - Chung, T.E.

AU - Du, K.

AU - Yeger, H.

AU - Beekman, J.M.

AU - Gonska, T.

AU - Bear, C.E.

PY - 2014

Y1 - 2014

U2 - 10.1016/j.chembiol.2014.02.021

DO - 10.1016/j.chembiol.2014.02.021

M3 - Article

C2 - 24726831

SN - 1074-5521

VL - 21

SP - 666

EP - 678

JO - Chemistry & Biology

JF - Chemistry & Biology

IS - 5

ER -