TY - JOUR
T1 - Virtual Resection
T2 - A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor Patients
AU - van der Zee, Jasper M.
AU - Fitski, Matthijs
AU - Simonis, Frank F.J.
AU - van de Ven, Cornelis P.
AU - Klijn, Aart J.
AU - Wijnen, Marc H.W.A.
AU - van der Steeg, Alida F.W.
N1 - Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/2/1
Y1 - 2022/2/1
N2 - Nephron-sparing surgery (NSS) in Wilms tumor (WT) patients is a surgically challenging procedure used in highly selective cases only. Virtual resections can be used for preoperative planning of NSS to estimate the remnant renal volume (RRV) and to virtually mimic radical tumor re-section. In this single-center evaluation study, virtual resection for NSS planning and the user experience were evaluated. Virtual resection was performed in nine WT patient cases by two pediatric surgeons and one pediatric urologist. Pre-and postoperative MRI scans were used for 3D visuali-zation. The virtual RRV was acquired after performing virtual resection and a questionnaire was used to assess the ease of use. The actual RRV was derived from the postoperative 3D visualization and compared with the derived virtual RRV. Virtual resection resulted in virtual RRVs that matched nearly perfectly with the actual RRVs. According to the questionnaire, virtual resection appeared to be straightforward and was not considered to be difficult. This study demonstrated the potential of virtual resection as a new planning tool to estimate the RRV after NSS in WT patients. Future research should further evaluate the clinical relevance of virtual resection by relating it to surgical outcome.
AB - Nephron-sparing surgery (NSS) in Wilms tumor (WT) patients is a surgically challenging procedure used in highly selective cases only. Virtual resections can be used for preoperative planning of NSS to estimate the remnant renal volume (RRV) and to virtually mimic radical tumor re-section. In this single-center evaluation study, virtual resection for NSS planning and the user experience were evaluated. Virtual resection was performed in nine WT patient cases by two pediatric surgeons and one pediatric urologist. Pre-and postoperative MRI scans were used for 3D visuali-zation. The virtual RRV was acquired after performing virtual resection and a questionnaire was used to assess the ease of use. The actual RRV was derived from the postoperative 3D visualization and compared with the derived virtual RRV. Virtual resection resulted in virtual RRVs that matched nearly perfectly with the actual RRVs. According to the questionnaire, virtual resection appeared to be straightforward and was not considered to be difficult. This study demonstrated the potential of virtual resection as a new planning tool to estimate the RRV after NSS in WT patients. Future research should further evaluate the clinical relevance of virtual resection by relating it to surgical outcome.
KW - Nephron-sparing surgery
KW - Partial nephrectomy
KW - Remnant renal parenchyma
KW - Remnant renal volume
KW - Virtual resection
KW - Wilms tumor
UR - http://www.scopus.com/inward/record.url?scp=85123934378&partnerID=8YFLogxK
U2 - 10.3390/curroncol29020066
DO - 10.3390/curroncol29020066
M3 - Article
C2 - 35200565
AN - SCOPUS:85123934378
SN - 1198-0052
VL - 29
SP - 777
EP - 784
JO - Current Oncology
JF - Current Oncology
IS - 2
ER -