Viral Infections

Linda S. de Vries; Sylke J. Steggerda

doi:10.1007/978-3-031-55972-3_12

Viral Infections

Linda S. de Vries^*, Sylke J. Steggerda

^*Corresponding author for this work

Birth Center Neonatology - Medical

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Abstract

Viral infections may occur during pregnancy, when the brain is developing, during birth, or within the first days to weeks after birth. This chapter describes the clinical and neuroimaging features of the most common congenital and postnatally acquired viral infections that can affect the fetal and neonatal brain. Cytomegalovirus is the most common congenital infection and can be associated with hearing loss and malformations of cortical development when occurring in the first trimester. Toxoplasmosis, a protozoan parasite, can lead to antenatal hydrocephalus. Postnatal infections are especially likely to affect the white matter, with a very similar pattern of injury for enterovirus, parechovirus, and rotavirus. The prognosis depends on the time of onset for the congenital infections and on the gestational age for the postnatal infections.

Original language	English
Title of host publication	Neonatal Brain Injury
Subtitle of host publication	An Illustrated Guide for Clinicians Counselling Parents and Caregivers
Publisher	Springer Nature
Pages	185-201
Number of pages	17
ISBN (Electronic)	9783031559723
ISBN (Print)	9783031559716
DOIs	https://doi.org/10.1007/978-3-031-55972-3_12
Publication status	Published - 1 Jan 2025

Keywords

CMV
Encephalitis
Enterovirus
Herpes simplex
Parechovirus
Rotavirus
TORCH
Toxoplasmosis

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Cite this

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abstract = "Viral infections may occur during pregnancy, when the brain is developing, during birth, or within the first days to weeks after birth. This chapter describes the clinical and neuroimaging features of the most common congenital and postnatally acquired viral infections that can affect the fetal and neonatal brain. Cytomegalovirus is the most common congenital infection and can be associated with hearing loss and malformations of cortical development when occurring in the first trimester. Toxoplasmosis, a protozoan parasite, can lead to antenatal hydrocephalus. Postnatal infections are especially likely to affect the white matter, with a very similar pattern of injury for enterovirus, parechovirus, and rotavirus. The prognosis depends on the time of onset for the congenital infections and on the gestational age for the postnatal infections.",

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KW - Herpes simplex

KW - Parechovirus

KW - Rotavirus

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KW - Toxoplasmosis

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Viral Infections

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