Viral evasion of the MHC class I antigen presentation pathway: It's a T(r)AP

Patrique Praest

doi:10.33540/552

Viral evasion of the MHC class I antigen presentation pathway: It's a T(r)AP

Patrique Praest

Department of Medical Microbiology

Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

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Abstract

Herpesviruses use a broad set of immune modulating mechanisms to escape the immune system; causing lifelong infections with these viruses. In this thesis we discuss newly identified interactions between viral evasins and host proteins and how these evasins influence essential processes in the host.

Original language	English
Awarding Institution	University Medical Center (UMC) Utrecht
Supervisors/Advisors	Wiertz, Emmanuel, Primary supervisor Lebbink, Robert Jan, Co-supervisor
Award date	13 May 2020
Publisher	Utrecht University
Print ISBNs	978-94-6380-800-2
DOIs	https://doi.org/10.33540/552
Publication status	Published - 13 May 2020

Keywords

Immune evasion
TAP
Herpesviruses
MHC I
Viruses
antigen presentation

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10.33540/552

11174praest patriquecomplete 2 - 603f57a78cccbFinal published version, 71.5 MB

https://dspace.library.uu.nl/handle/1874/401920

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KW - Immune evasion

KW - TAP

KW - Herpesviruses

KW - MHC I

KW - Viruses

KW - antigen presentation

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M3 - Doctoral thesis 1 (Research UU / Graduation UU)

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PB - Utrecht University

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Viral evasion of the MHC class I antigen presentation pathway: It's a T(r)AP

Abstract

Keywords

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