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Vertebral bone destruction in sickle cell disease: Infection, infarction or both

  • A. Kooy*
  • , L. J.M. De Heide
  • , A. J. Ten Tije
  • , A. H. Mulder
  • , H. L.J. Tanghe
  • , J. A.J.W. Kluytmans
  • , J. J. Michiels
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Abstract

Infectious and vaso-occlusive vertebral bone and joint destruction in two patients with sickle cell disease (SCD) are featured by H-shaped vertebrae, kyphotic angulation, osteolysis of endplates and collapse of intervertebral discs as shown by X-ray films and magnetic resonance imaging. Staphylococcal serology supported the diagnosis of staphylococcal osteomyelitis/spondylo-discitis in both SCD patients. The difficulties of establishing the causes and treatment of the osteoarthropathy in these particular cases are discussed in the light of the literature.

Original languageEnglish
Pages (from-to)227-230
Number of pages4
JournalNetherlands Journal of Medicine
Volume48
Issue number6
DOIs
Publication statusPublished - Jun 1996
Externally publishedYes

Keywords

  • Bone infarctions
  • Osteomyelitis
  • Septic arthritis
  • Sickle cell disease

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