Validity of a clinical model to predict influenza in patients presenting with symptoms of lower respiratory tract infection in primary care

Saskia F. de Vries-van Vugt*, Berna D L Broekhuizen, Nicolaas P A Zuithoff, Gerrit A. van Essen, Mark H. Ebell, Samuel Coenen, Margareta Ieven, Christine Lammens, Herman Goossens, Chris C. Butler, Kerenza Hood, Paul Littleg, Theo J M Verheij, Peter Zuithoff, Ted van Essen, Jordi Almirall, Francesco Blasi, Slawomir Chlabicz, Mel Davies, Maciek Godycki-CwirkoHelena Hupkova, Janko Kersnik, Artur Mierzecki, Sigvard Mölstad, Michael Moore, Tom Schaberg, An de Sutter, Antoni Torres, Pia Touboul, Paul Little, Theo Verheij

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background. Valid clinical predictors of influenza in patients presenting with lower respiratory tract infection (LRTI) symptoms would provide adequate patient information and reassurance. Aim. Assessing the validity of an existing diagnostic model (Flu Score) to detect influenza in LRTI patients. Design and Setting. A European diagnostic study recruited 1801 adult primary care patients with LRTI-like symptoms existing ≤7 days between October and April 2007-2010. Method. History and physical examination findings were recorded and nasopharyngeal swabs taken. Polymerase chain reaction (PCR) for influenza A/B was performed as reference test. Diagnostic accuracy of the Flu Score (1× onset

Original languageEnglish
Pages (from-to)408-414
Number of pages7
JournalFamily Practice
Volume32
Issue number4
DOIs
Publication statusPublished - 1 Aug 2015

Keywords

  • Cough
  • Diagnostic accuracy
  • Europe
  • Influenza
  • Lower respiratory tract infection
  • Primary health care

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