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Validation of prevalent diabetes risk scores based on non-invasively measured predictors in Ghanaian migrant and non-migrant populations – The RODAM study

  • James Osei-Yeboah*
  • , Andre-Pascal Kengne
  • , Ellis Owusu-Dabo
  • , Matthias B. Schulze
  • , Karlijn A.C. Meeks
  • , Kerstin Klipstein-Grobusch
  • , Liam Smeeth
  • , Silver Bahendeka
  • , Erik Beune
  • , Eric P. Moll van Charante
  • , Charles Agyemang
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Background Non-invasive diabetes risk models are a cost-effective tool in large-scale population screening to identify those who need confirmation tests, especially in resource-limited settings. Aims This study aimed to evaluate the ability of six non-invasive risk models (Cambridge, FINDRISC, Kuwaiti, Omani, Rotterdam, and SUNSET model) to identify screen-detected diabetes (defined by HbA1c) among Ghanaian migrants and non-migrants. Study design A multicentered cross-sectional study. Methods This analysis included 4843 Ghanaian migrants and non-migrants from the Research on Obesity and Diabetes among African Migrants (RODAM) Study. Model performance was assessed using the area under the receiver operating characteristic curves (AUC), Hosmer-Lemeshow statistics, and calibration plots. Results All six models had acceptable discrimination (0.70 ≤ AUC
Original languageEnglish
Article number100453
JournalPublic health in practice
Volume6
DOIs
Publication statusPublished - Dec 2023

Keywords

  • Diabetes risk prediction
  • External validation
  • Migrant population
  • Sub-Saharan Africa population

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