Uncovering the genomic toll of the Black Death

Jonas Kuiper; Peter van Endert

doi:10.1016/j.it.2022.12.001

Uncovering the genomic toll of the Black Death

Jonas Kuiper
, Peter van Endert^*

^*Corresponding author for this work

Infection & Immunity

Research output: Contribution to journal › Short survey › peer-review

Abstract

The Black Death, a notorious devastating pandemic caused by Yersinia pestis infection during the 14th century, posed a formidable challenge to human immune defenses. A new article by Klunk et al. reports that a variant in an antigen-processing gene may have favored survival during the plague and may have undergone genomic selection in Europeans at unprecedented speed.

Original language	English
Pages (from-to)	90-92
Number of pages	3
Journal	Trends in immunology
Volume	44
Issue number	2
DOIs	https://doi.org/10.1016/j.it.2022.12.001
Publication status	Published - Feb 2023

Keywords

Antigen Presentation
Genomics
Humans
Pandemics
Plague/epidemiology
Yersinia pestis/genetics

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10.1016/j.it.2022.12.001

1-s2.0-S1471490622002587-mainFinal published version, 375 KBLicence: Taverne

Cite this

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KW - Antigen Presentation

KW - Genomics

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KW - Pandemics

KW - Plague/epidemiology

KW - Yersinia pestis/genetics

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Uncovering the genomic toll of the Black Death

Abstract

Keywords

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