Tumour-bound RNA-laden exosomes

Sander A.A. Kooijmans; Pieter Vader; Raymond M. Schiffelers

doi:10.1038/s41551-017-0119-4

Tumour-bound RNA-laden exosomes

Sander A.A. Kooijmans
, Pieter Vader
, Raymond M. Schiffelers^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

Abstract

Exosomes expressing CD47 and loaded with interfering RNA dodge phagocytosis and accumulate in pancreatic tumours to silence the expression of the oncogene Kras in mice, with remarkable therapeutic efficacy.

Original language	English
Pages (from-to)	634-636
Number of pages	3
Journal	Nature biomedical engineering
Volume	1
Issue number	8
DOIs	https://doi.org/10.1038/s41551-017-0119-4
Publication status	Published - Aug 2017

Access to Document

10.1038/s41551-017-0119-4

Cite this

@article{e3bff739c73240f8a5da1d3840929684,

title = "Tumour-bound RNA-laden exosomes",

abstract = "Exosomes expressing CD47 and loaded with interfering RNA dodge phagocytosis and accumulate in pancreatic tumours to silence the expression of the oncogene Kras in mice, with remarkable therapeutic efficacy.",

author = "Kooijmans, \{Sander A.A.\} and Pieter Vader and Schiffelers, \{Raymond M.\}",

year = "2017",

month = aug,

doi = "10.1038/s41551-017-0119-4",

language = "English",

volume = "1",

pages = "634--636",

journal = "Nature biomedical engineering",

publisher = "Nature Publishing Group",

number = "8",

}

TY - JOUR

T1 - Tumour-bound RNA-laden exosomes

AU - Kooijmans, Sander A.A.

AU - Vader, Pieter

AU - Schiffelers, Raymond M.

PY - 2017/8

Y1 - 2017/8

N2 - Exosomes expressing CD47 and loaded with interfering RNA dodge phagocytosis and accumulate in pancreatic tumours to silence the expression of the oncogene Kras in mice, with remarkable therapeutic efficacy.

AB - Exosomes expressing CD47 and loaded with interfering RNA dodge phagocytosis and accumulate in pancreatic tumours to silence the expression of the oncogene Kras in mice, with remarkable therapeutic efficacy.

UR - https://www.scopus.com/pages/publications/85031936534

U2 - 10.1038/s41551-017-0119-4

DO - 10.1038/s41551-017-0119-4

M3 - Short survey

AN - SCOPUS:85031936534

VL - 1

SP - 634

EP - 636

JO - Nature biomedical engineering

JF - Nature biomedical engineering

IS - 8

ER -

Tumour-bound RNA-laden exosomes

Abstract

Access to Document

Other files and links

Fingerprint

Cite this