Tumour-bound RNA-laden exosomes

Sander A.A. Kooijmans, Pieter Vader, Raymond M. Schiffelers*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

Abstract

Exosomes expressing CD47 and loaded with interfering RNA dodge phagocytosis and accumulate in pancreatic tumours to silence the expression of the oncogene Kras in mice, with remarkable therapeutic efficacy.
Original languageEnglish
Pages (from-to)634-636
Number of pages3
JournalNature Biomedical Engineering
Volume1
Issue number8
DOIs
Publication statusPublished - Aug 2017

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