@article{7196835da83c4a29a1b279434297d69d,
title = "Trends and patterns of computed tomography scan use among children in The Netherlands: 1990–2012",
abstract = "Objective: To evaluate trends and patterns in CT usage among children (aged 0–17 years) in The Netherlands during the period 1990–2012. Methods: Lists of electronically archived paediatric CT scans were requested from the Radiology Information Systems (RIS) of Dutch hospitals which reported >10 paediatric CT scans annually in a survey conducted in 2010. Data included patient identification, birth date, gender, scan date and body part scanned. For non-participating hospitals and for years prior to electronic archiving in some participating hospitals, data were imputed by calendar year and hospital type (academic, general with ",
keywords = "Child, Computed tomography, Paediatric, Patterns, Trends",
author = "Meulepas, {Johanna M.} and Smets, {Anne M J B} and Nievelstein, {Rutger A J} and Patrycja Gradowska and Jonathan Verbeke and Holscher, {Herma C.} and Rutten, {Matthieu J C M} and Mari{\"e}tte Kieft and Ronckers, {C{\'e}cile M.} and Michael Hauptmann",
note = "Funding Information: The scientific guarantor of this publication is Dr. M. Hauptmann. The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article. This study has received funding by the European Community Seventh Framework Programme [grant number FP7/2007-2013] under Grant Agreement Number 269912-EPI-CT: {\textquoteleft}Epidemiological study to quantify risks for paediatric computerized tomography and to optimize doses{\textquoteright} and by Worldwide Cancer Research formerly known as Association for International Cancer Research (AICR) [grant number 12-1155]. Dr. Cecile Ronckers is supported by the Dutch Cancer Society. Funders had no involvement in the study design, data collection, analysis and interpretation, the writing of the report, or the decision to submit the paper for publication. One of the authors has significant statistical expertise (p < 0.001). Institutional Review Board approval and written informed consent was not required because the study concerns secondary use of personal and medical data from medical files. In The Netherlands, a self-regulatory Code of Conduct for the use of data in Health Research generally mandates explicit written individual patient consent to the physician to authorize release of personal medical information for scientific purposes. In compliance with the Code, radiologists are nonetheless allowed to provide data without consent, because (1) the resources needed to trace large cohorts render research infeasible, (2) a high potential of selective participation leading to biased cancer risk and loss of statistical power, and (3) the study invitation letter likely causes worries among children and parents, particularly because it cannot take the individual indication (and justification) for a CT scan into account. In compliance with the Code of Conduct, we prepared a data protection regulation document and defined data flow and data access policies. Methodology: retrospective, observational, multicentre study. Publisher Copyright: {\textcopyright} 2016, European Society of Radiology.",
year = "2017",
month = jun,
doi = "10.1007/s00330-016-4566-1",
language = "English",
volume = "27",
pages = "2426–2433",
journal = "European Radiology",
issn = "0938-7994",
publisher = "Springer-Verlag",
number = "6",
}