Treatment robustness of total body irradiation with volumetric modulated arc therapy

Enrica Seravalli; Mirjam Willemsen-Bosman; Annelies Zoetelief; Sanne Roosenboom; Tessa Harderwijk; Lean Krikke; Gijsbert Bol; Alexis Kotte; Eline Huijboom; Karel van Loon; Bianca Hoeben

doi:10.1016/j.phro.2024.100537

Treatment robustness of total body irradiation with volumetric modulated arc therapy

Enrica Seravalli^*
, Mirjam Willemsen-Bosman
, Annelies Zoetelief
, Sanne Roosenboom
, Tessa Harderwijk
, Lean Krikke
, Gijsbert Bol
, Alexis Kotte
, Eline Huijboom
, Karel van Loon
, Bianca Hoeben

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

This study evaluated the robustness of multi-isocenter Volumetric Modulated Arc Therapy Total Body Irradiation dose distribution in the overlapping region between the head-first and feet-first computed tomography scans, considering the longitudinal isocenter shifts recorded during treatment delivery. For 15 out of 22 patients, the dose distribution in the overlapping region fulfilled all three the robustness criteria. The overlapping region dose distribution of the remaining 7 cases fulfilled two robustness criteria. The dose distribution was found to be robust against daily recorded longitudinal isocenter shifts, as a consequence of the patient position verification procedure, of up to 16 mm.

Original language	English
Article number	100537
Number of pages	4
Journal	Physics and Imaging in Radiation Oncology
Volume	29
DOIs	https://doi.org/10.1016/j.phro.2024.100537
Publication status	Published - Jan 2024

Keywords

Conformal radiotherapy techniques
Junction
Patient position verification
Robustness
TBI
Total body irradiation
VMAT

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10.1016/j.phro.2024.100537Licence: CC BY

PIIS2405631624000071Final published version, 393 KBLicence: CC BY

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title = "Treatment robustness of total body irradiation with volumetric modulated arc therapy",

abstract = "This study evaluated the robustness of multi-isocenter Volumetric Modulated Arc Therapy Total Body Irradiation dose distribution in the overlapping region between the head-first and feet-first computed tomography scans, considering the longitudinal isocenter shifts recorded during treatment delivery. For 15 out of 22 patients, the dose distribution in the overlapping region fulfilled all three the robustness criteria. The overlapping region dose distribution of the remaining 7 cases fulfilled two robustness criteria. The dose distribution was found to be robust against daily recorded longitudinal isocenter shifts, as a consequence of the patient position verification procedure, of up to 16 mm.",

keywords = "Conformal radiotherapy techniques, Junction, Patient position verification, Robustness, TBI, Total body irradiation, VMAT",

author = "Enrica Seravalli and Mirjam Willemsen-Bosman and Annelies Zoetelief and Sanne Roosenboom and Tessa Harderwijk and Lean Krikke and Gijsbert Bol and Alexis Kotte and Eline Huijboom and \{van Loon\}, Karel and Bianca Hoeben",

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doi = "10.1016/j.phro.2024.100537",

language = "English",

volume = "29",

journal = "Physics and Imaging in Radiation Oncology",

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T1 - Treatment robustness of total body irradiation with volumetric modulated arc therapy

AU - Seravalli, Enrica

AU - Willemsen-Bosman, Mirjam

AU - Zoetelief, Annelies

AU - Roosenboom, Sanne

AU - Harderwijk, Tessa

AU - Krikke, Lean

AU - Bol, Gijsbert

AU - Kotte, Alexis

AU - Huijboom, Eline

AU - van Loon, Karel

AU - Hoeben, Bianca

PY - 2024/1

Y1 - 2024/1

N2 - This study evaluated the robustness of multi-isocenter Volumetric Modulated Arc Therapy Total Body Irradiation dose distribution in the overlapping region between the head-first and feet-first computed tomography scans, considering the longitudinal isocenter shifts recorded during treatment delivery. For 15 out of 22 patients, the dose distribution in the overlapping region fulfilled all three the robustness criteria. The overlapping region dose distribution of the remaining 7 cases fulfilled two robustness criteria. The dose distribution was found to be robust against daily recorded longitudinal isocenter shifts, as a consequence of the patient position verification procedure, of up to 16 mm.

AB - This study evaluated the robustness of multi-isocenter Volumetric Modulated Arc Therapy Total Body Irradiation dose distribution in the overlapping region between the head-first and feet-first computed tomography scans, considering the longitudinal isocenter shifts recorded during treatment delivery. For 15 out of 22 patients, the dose distribution in the overlapping region fulfilled all three the robustness criteria. The overlapping region dose distribution of the remaining 7 cases fulfilled two robustness criteria. The dose distribution was found to be robust against daily recorded longitudinal isocenter shifts, as a consequence of the patient position verification procedure, of up to 16 mm.

KW - Conformal radiotherapy techniques

KW - Junction

KW - Patient position verification

KW - Robustness

KW - TBI

KW - Total body irradiation

KW - VMAT

UR - https://www.scopus.com/pages/publications/85182391586

U2 - 10.1016/j.phro.2024.100537

DO - 10.1016/j.phro.2024.100537

M3 - Article

AN - SCOPUS:85182391586

SN - 2405-6316

VL - 29

JO - Physics and Imaging in Radiation Oncology

JF - Physics and Imaging in Radiation Oncology

M1 - 100537

ER -

Treatment robustness of total body irradiation with volumetric modulated arc therapy

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