Treatment planning of boron neutron capture therapy: Measurements and calculations

M. W. Konijnenberg; C. P.J. Raaijmakers; L. Dewit; B. J. Mijnheer; R. L. Moss; F. Stecher-Rasmussen; P. R.D. Watkins

doi:10.1093/rpd/44.1-4.443

Treatment planning of boron neutron capture therapy: Measurements and calculations

M. W. Konijnenberg^*, C. P.J. Raaijmakers, L. Dewit, B. J. Mijnheer, R. L. Moss, F. Stecher-Rasmussen, P. R.D. Watkins

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

Abstract

A clinical boron neutron capture therapy (BNCT) facility, employing a high intensity epithermal neutron beam, has recently become available at the High Flux Reactor (HFR) in Petten. Another epithermal beam has been constructed at the Low Flux Reactor (LFR) to test the behaviour of a mixed epithermal neutron and photon field in water phantoms. The neutron and photon fluence distributions have been measured with a BF₃ counter and a ²³⁵U fission counter and with a GM counter and a Mg(Ar) ionisation chamber, respectively. Absolute determination of the neutron fluence has been performed with foil stacks and of the gamma ray dose with TLD chips. For the design of a treatment planning system for BNCT, the use of a Monte Carlo technique has been investigated. The outcome of these calculations fits the measurements within 1%.

Original language	English
Pages (from-to)	443-446
Number of pages	4
Journal	Radiation Protection Dosimetry
Volume	44
Issue number	1-4
DOIs	https://doi.org/10.1093/rpd/44.1-4.443
Publication status	Published - 1992
Externally published	Yes

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abstract = "A clinical boron neutron capture therapy (BNCT) facility, employing a high intensity epithermal neutron beam, has recently become available at the High Flux Reactor (HFR) in Petten. Another epithermal beam has been constructed at the Low Flux Reactor (LFR) to test the behaviour of a mixed epithermal neutron and photon field in water phantoms. The neutron and photon fluence distributions have been measured with a BF3 counter and a 235U fission counter and with a GM counter and a Mg(Ar) ionisation chamber, respectively. Absolute determination of the neutron fluence has been performed with foil stacks and of the gamma ray dose with TLD chips. For the design of a treatment planning system for BNCT, the use of a Monte Carlo technique has been investigated. The outcome of these calculations fits the measurements within 1%.",

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AU - Konijnenberg, M. W.

AU - Raaijmakers, C. P.J.

AU - Dewit, L.

AU - Mijnheer, B. J.

AU - Moss, R. L.

AU - Stecher-Rasmussen, F.

AU - Watkins, P. R.D.

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Treatment planning of boron neutron capture therapy: Measurements and calculations

Abstract

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