TY - JOUR
T1 - Treatment of patients with long-standing unexplained subfertility with in vitro fertilization
AU - Donderwinkel, Peter F.
AU - Van Der Vaart, Hester
AU - Wolters, Victorien M.
AU - Simons, Arnold H.
AU - Kroon, Gerard
AU - Heineman, Maas Jan
PY - 2000/1/1
Y1 - 2000/1/1
N2 - Objective: To evaluate whether IVF is an effective treatment for long-standing unexplained subfertility.Design: Retrospective cohort study.Setting: Tertiary care infertility center in a university hospital.Patient(s): Two hundred two couples with unexplained subfertility of 2 years’ duration or more who attended the center for their first IVF attempt.Intervention(s): Couples were placed on a waiting list for IVF. They received no treatment until IVF was started.Main Outcome Measure(s): Pregnancy rate (PR) while on the waiting list and PR after IVF treatment.Result(s): Complete data sets were available for 131 couples. Seventeen of 131 women became pregnant while waiting for IVF treatment (PR 0.9% per exposure cycle), whereas 45 of 119 receiving IVF treatment became pregnant (PR 17% per IVF attempt).Conclusion(s): IVF treatment has substantial added value over waiting and is an efficient treatment for long-standing unexplained subfertility.
AB - Objective: To evaluate whether IVF is an effective treatment for long-standing unexplained subfertility.Design: Retrospective cohort study.Setting: Tertiary care infertility center in a university hospital.Patient(s): Two hundred two couples with unexplained subfertility of 2 years’ duration or more who attended the center for their first IVF attempt.Intervention(s): Couples were placed on a waiting list for IVF. They received no treatment until IVF was started.Main Outcome Measure(s): Pregnancy rate (PR) while on the waiting list and PR after IVF treatment.Result(s): Complete data sets were available for 131 couples. Seventeen of 131 women became pregnant while waiting for IVF treatment (PR 0.9% per exposure cycle), whereas 45 of 119 receiving IVF treatment became pregnant (PR 17% per IVF attempt).Conclusion(s): IVF treatment has substantial added value over waiting and is an efficient treatment for long-standing unexplained subfertility.
KW - IVF treatment
KW - No treatment
KW - Retrospective cohort study
KW - Unexplained subfertility
KW - Waiting list
UR - http://www.scopus.com/inward/record.url?scp=0033964451&partnerID=8YFLogxK
U2 - 10.1016/S0015-0282(99)00518-X
DO - 10.1016/S0015-0282(99)00518-X
M3 - Article
C2 - 10685539
AN - SCOPUS:0033964451
SN - 0015-0282
VL - 73
SP - 334
EP - 337
JO - Fertility and Sterility
JF - Fertility and Sterility
IS - 2
ER -