Treatment of central giant cell granuloma of the jaw with calcitonin

J. De Lange; A. J W P Rosenberg; H. P. Van Den Akker; R. Koole; J. J. Wirds; H. Van Den Berg

Treatment of central giant cell granuloma of the jaw with calcitonin

J. De Lange^*, A. J W P Rosenberg, H. P. Van Den Akker, R. Koole, J. J. Wirds, H. Van Den Berg

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

74 Citations (Scopus)

Abstract

Giant cell granuloma of the jaw is a benign lesion that may cause local destruction of bone and displacement of teeth. The common therapy is curettage or resection, which may be associated with loss of teeth and, in younger patients, loss of dental germs. An alternative treatment has recently been introduced, in which patients receive a daily dose of calcitonin. Four patients who have been treated with calcitonin in various concentrations for at least 1 year are reported. In all patients, complete remission of the giant cell granuloma was observed, without signs of recurrence. The working mechanism of calcitonin is discussed, as are length of treatment and optimal dose.

Original language	English
Pages (from-to)	372-376
Number of pages	5
Journal	International Journal of Oral and Maxillofacial Surgery
Volume	28
Issue number	5
Publication status	Published - Oct 1999

Keywords

Calcitonin
Central giant cell granuloma
Osteoclast

Cite this

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title = "Treatment of central giant cell granuloma of the jaw with calcitonin",

abstract = "Giant cell granuloma of the jaw is a benign lesion that may cause local destruction of bone and displacement of teeth. The common therapy is curettage or resection, which may be associated with loss of teeth and, in younger patients, loss of dental germs. An alternative treatment has recently been introduced, in which patients receive a daily dose of calcitonin. Four patients who have been treated with calcitonin in various concentrations for at least 1 year are reported. In all patients, complete remission of the giant cell granuloma was observed, without signs of recurrence. The working mechanism of calcitonin is discussed, as are length of treatment and optimal dose.",

keywords = "Calcitonin, Central giant cell granuloma, Osteoclast",

author = "{De Lange}, J. and Rosenberg, {A. J W P} and {Van Den Akker}, {H. P.} and R. Koole and Wirds, {J. J.} and {Van Den Berg}, H.",

year = "1999",

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language = "English",

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T1 - Treatment of central giant cell granuloma of the jaw with calcitonin

AU - De Lange, J.

AU - Rosenberg, A. J W P

AU - Van Den Akker, H. P.

AU - Koole, R.

AU - Wirds, J. J.

AU - Van Den Berg, H.

PY - 1999/10

Y1 - 1999/10

N2 - Giant cell granuloma of the jaw is a benign lesion that may cause local destruction of bone and displacement of teeth. The common therapy is curettage or resection, which may be associated with loss of teeth and, in younger patients, loss of dental germs. An alternative treatment has recently been introduced, in which patients receive a daily dose of calcitonin. Four patients who have been treated with calcitonin in various concentrations for at least 1 year are reported. In all patients, complete remission of the giant cell granuloma was observed, without signs of recurrence. The working mechanism of calcitonin is discussed, as are length of treatment and optimal dose.

AB - Giant cell granuloma of the jaw is a benign lesion that may cause local destruction of bone and displacement of teeth. The common therapy is curettage or resection, which may be associated with loss of teeth and, in younger patients, loss of dental germs. An alternative treatment has recently been introduced, in which patients receive a daily dose of calcitonin. Four patients who have been treated with calcitonin in various concentrations for at least 1 year are reported. In all patients, complete remission of the giant cell granuloma was observed, without signs of recurrence. The working mechanism of calcitonin is discussed, as are length of treatment and optimal dose.

KW - Calcitonin

KW - Central giant cell granuloma

KW - Osteoclast

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AN - SCOPUS:0033212226

SN - 0901-5027

VL - 28

SP - 372

EP - 376

JO - International Journal of Oral and Maxillofacial Surgery

JF - International Journal of Oral and Maxillofacial Surgery

IS - 5

ER -

Treatment of central giant cell granuloma of the jaw with calcitonin

Abstract

Keywords

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