Transmission of respiratory syncytial virus at the paediatric intensive-care unit: a prospective study using real-time PCR

A.C. van de Pol; J.W.A. Rossen; T.F.W. Wolfs; E.K. Breteler; J.L.L. Kimpen; A.M. van Loon; N.J.G. Jansen

doi:10.1111/j.1469-0691.2009.02854.x

Transmission of respiratory syncytial virus at the paediatric intensive-care unit: a prospective study using real-time PCR

A.C. van de Pol, J.W.A. Rossen, T.F.W. Wolfs, E.K. Breteler, J.L.L. Kimpen, A.M. van Loon, N.J.G. Jansen

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Transmission of respiratory syncytial virus (RSV) from children with lower respiratory tract infection (LRTI) at a paediatric intensive-care unit (PICU) was examined using a highly sensitive real-time PCR. Twenty-four children with RSV LRTI were admitted during the study period (total days of potential transmission: 239). Forty-eight RSV-negative patients were followed up for RSV acquisition every 5 days (total days of exposure: 683). No single RSV transmission was documented with this highly sensitive diagnostic method. Therefore, routine infection control measures of LRTI patients seem to be adequate to prevent RSV transmission at the PICU.

Original language	English
Pages (from-to)	488-490
Number of pages	3
Journal	Clinical Microbiology and Infection
Volume	16
Issue number	5
DOIs	https://doi.org/10.1111/j.1469-0691.2009.02854.x
Publication status	Published - 2010

Keywords

Child
Cross Infection
Humans
Intensive Care Units, Pediatric
Polymerase Chain Reaction
Prospective Studies
Respiratory Syncytial Virus Infections
Respiratory Syncytial Viruses

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10.1111/j.1469-0691.2009.02854.x

http://www.ncbi.nlm.nih.gov/pubmed/19523052

Cite this

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title = "Transmission of respiratory syncytial virus at the paediatric intensive-care unit: a prospective study using real-time PCR",

abstract = "Transmission of respiratory syncytial virus (RSV) from children with lower respiratory tract infection (LRTI) at a paediatric intensive-care unit (PICU) was examined using a highly sensitive real-time PCR. Twenty-four children with RSV LRTI were admitted during the study period (total days of potential transmission: 239). Forty-eight RSV-negative patients were followed up for RSV acquisition every 5 days (total days of exposure: 683). No single RSV transmission was documented with this highly sensitive diagnostic method. Therefore, routine infection control measures of LRTI patients seem to be adequate to prevent RSV transmission at the PICU.",

keywords = "Child, Cross Infection, Humans, Intensive Care Units, Pediatric, Polymerase Chain Reaction, Prospective Studies, Respiratory Syncytial Virus Infections, Respiratory Syncytial Viruses",

author = "{van de Pol}, A.C. and J.W.A. Rossen and T.F.W. Wolfs and E.K. Breteler and J.L.L. Kimpen and {van Loon}, A.M. and N.J.G. Jansen",

year = "2010",

doi = "10.1111/j.1469-0691.2009.02854.x",

language = "English",

volume = "16",

pages = "488--490",

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TY - JOUR

T1 - Transmission of respiratory syncytial virus at the paediatric intensive-care unit

T2 - a prospective study using real-time PCR

AU - van de Pol, A.C.

AU - Rossen, J.W.A.

AU - Wolfs, T.F.W.

AU - Breteler, E.K.

AU - Kimpen, J.L.L.

AU - van Loon, A.M.

AU - Jansen, N.J.G.

PY - 2010

Y1 - 2010

N2 - Transmission of respiratory syncytial virus (RSV) from children with lower respiratory tract infection (LRTI) at a paediatric intensive-care unit (PICU) was examined using a highly sensitive real-time PCR. Twenty-four children with RSV LRTI were admitted during the study period (total days of potential transmission: 239). Forty-eight RSV-negative patients were followed up for RSV acquisition every 5 days (total days of exposure: 683). No single RSV transmission was documented with this highly sensitive diagnostic method. Therefore, routine infection control measures of LRTI patients seem to be adequate to prevent RSV transmission at the PICU.

AB - Transmission of respiratory syncytial virus (RSV) from children with lower respiratory tract infection (LRTI) at a paediatric intensive-care unit (PICU) was examined using a highly sensitive real-time PCR. Twenty-four children with RSV LRTI were admitted during the study period (total days of potential transmission: 239). Forty-eight RSV-negative patients were followed up for RSV acquisition every 5 days (total days of exposure: 683). No single RSV transmission was documented with this highly sensitive diagnostic method. Therefore, routine infection control measures of LRTI patients seem to be adequate to prevent RSV transmission at the PICU.

KW - Child

KW - Cross Infection

KW - Humans

KW - Intensive Care Units, Pediatric

KW - Polymerase Chain Reaction

KW - Prospective Studies

KW - Respiratory Syncytial Virus Infections

KW - Respiratory Syncytial Viruses

U2 - 10.1111/j.1469-0691.2009.02854.x

DO - 10.1111/j.1469-0691.2009.02854.x

M3 - Article

C2 - 19523052

SN - 1198-743X

VL - 16

SP - 488

EP - 490

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

IS - 5

ER -

Transmission of respiratory syncytial virus at the paediatric intensive-care unit: a prospective study using real-time PCR

Abstract

Keywords

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