Transmission dynamics of low- and high-pathogenicity A/Chicken/Pennsylvania/83 avian influenza viruses

J A van der Goot; G Koch; M C M de Jong; M van Boven

doi:10.1637/0005-2086-47.s3.939

Transmission dynamics of low- and high-pathogenicity A/Chicken/Pennsylvania/83 avian influenza viruses

J A van der Goot
, G Koch
, M C M de Jong
, M van Boven

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

High-pathogenicity avian influenza (HPAI) viruses emerged from low-pathogenicity avian influenza (LPAI) viruses in Pennsylvania (1983-84), Mexico (1994-95), and Italy (1999-2000). Here we focus on the question of why the HPAI virus supersedes the LPAI virus, once it has appeared during the epidemic. To study this, we used an experimental model in chickens that enabled us to estimate the reproduction ratio (R0). Using this model, we determined the R0 of the A/Chicken/Pennsylvania/21525/83 (LPAI) and of the A/Chicken/Pennsylvania/1370/83 (HPAI). Comparing the R0 of both viruses, we concluded that the R0 of the HPAI virus is significantly higher than the R0 of the LPAI.

Original language	English
Pages (from-to)	939-41
Number of pages	3
Journal	Avian diseases
Volume	47
Issue number	3 Suppl
DOIs	https://doi.org/10.1637/0005-2086-47.s3.939
Publication status	Published - 2003
Externally published	Yes

Keywords

Animals
Chickens
Influenza A virus/classification
Influenza in Birds/transmission
Pennsylvania

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10.1637/0005-2086-47.s3.939

Cite this

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title = "Transmission dynamics of low- and high-pathogenicity A/Chicken/Pennsylvania/83 avian influenza viruses",

abstract = "High-pathogenicity avian influenza (HPAI) viruses emerged from low-pathogenicity avian influenza (LPAI) viruses in Pennsylvania (1983-84), Mexico (1994-95), and Italy (1999-2000). Here we focus on the question of why the HPAI virus supersedes the LPAI virus, once it has appeared during the epidemic. To study this, we used an experimental model in chickens that enabled us to estimate the reproduction ratio (R0). Using this model, we determined the R0 of the A/Chicken/Pennsylvania/21525/83 (LPAI) and of the A/Chicken/Pennsylvania/1370/83 (HPAI). Comparing the R0 of both viruses, we concluded that the R0 of the HPAI virus is significantly higher than the R0 of the LPAI.",

keywords = "Animals, Chickens, Influenza A virus/classification, Influenza in Birds/transmission, Pennsylvania",

author = "\{van der Goot\}, \{J A\} and G Koch and \{de Jong\}, \{M C M\} and \{van Boven\}, M",

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doi = "10.1637/0005-2086-47.s3.939",

language = "English",

volume = "47",

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TY - JOUR

T1 - Transmission dynamics of low- and high-pathogenicity A/Chicken/Pennsylvania/83 avian influenza viruses

AU - van der Goot, J A

AU - Koch, G

AU - de Jong, M C M

AU - van Boven, M

PY - 2003

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N2 - High-pathogenicity avian influenza (HPAI) viruses emerged from low-pathogenicity avian influenza (LPAI) viruses in Pennsylvania (1983-84), Mexico (1994-95), and Italy (1999-2000). Here we focus on the question of why the HPAI virus supersedes the LPAI virus, once it has appeared during the epidemic. To study this, we used an experimental model in chickens that enabled us to estimate the reproduction ratio (R0). Using this model, we determined the R0 of the A/Chicken/Pennsylvania/21525/83 (LPAI) and of the A/Chicken/Pennsylvania/1370/83 (HPAI). Comparing the R0 of both viruses, we concluded that the R0 of the HPAI virus is significantly higher than the R0 of the LPAI.

AB - High-pathogenicity avian influenza (HPAI) viruses emerged from low-pathogenicity avian influenza (LPAI) viruses in Pennsylvania (1983-84), Mexico (1994-95), and Italy (1999-2000). Here we focus on the question of why the HPAI virus supersedes the LPAI virus, once it has appeared during the epidemic. To study this, we used an experimental model in chickens that enabled us to estimate the reproduction ratio (R0). Using this model, we determined the R0 of the A/Chicken/Pennsylvania/21525/83 (LPAI) and of the A/Chicken/Pennsylvania/1370/83 (HPAI). Comparing the R0 of both viruses, we concluded that the R0 of the HPAI virus is significantly higher than the R0 of the LPAI.

KW - Animals

KW - Chickens

KW - Influenza A virus/classification

KW - Influenza in Birds/transmission

KW - Pennsylvania

U2 - 10.1637/0005-2086-47.s3.939

DO - 10.1637/0005-2086-47.s3.939

M3 - Article

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SN - 0005-2086

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SP - 939

EP - 941

JO - Avian diseases

JF - Avian diseases

IS - 3 Suppl

ER -

Transmission dynamics of low- and high-pathogenicity A/Chicken/Pennsylvania/83 avian influenza viruses

Abstract

Keywords

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