Towards MRI-guided rectal cancer boost radiotherapy

J.-P.J.E. Kleijnen

Research output: ThesisDoctoral thesis 1 (Research UU / Graduation UU)

Abstract

This thesis focuses on filling the knowledge gaps for an effective introduction of MRI-guided boost treatments for rectal cancer. Also existing knowledge on CTV motion is redefined, using the benefits of MRI’s superior soft tissue contrast, thereby improving the standard treatment.
In this thesis the preparatory steps for introduction of MRI-guided radiotherapy in rectal cancer are discussed. These steps include evaluating the limitations of the current standard of care CT-guided treatment and assessing where MRI-guided radiotherapy can reduce these limitations by using the benefits of the superior soft tissue contrast of the MRI.
Original languageEnglish
Awarding Institution
  • University Medical Center (UMC) Utrecht
Supervisors/Advisors
  • Raaymakers, Bas, Primary supervisor
  • Lagendijk, JJW, Supervisor
  • van Asselen, B., Co-supervisor
  • Intven, Martijn, Co-supervisor
Award date11 Jul 2019
Place of Publication[Utrecht]
Publisher
Print ISBNs978-94-6380-417-2
Publication statusPublished - 11 Jul 2019

Keywords

  • radiotherapy
  • rectal cancer
  • MRI
  • dose escalation

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