Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study

Sander Banus; Renske W B Bottema; Christine L E Siezen; Rob J. Vandebriel; Johan Reimerink; Monique Mommers; Gerard H. Koppelman; Barbara Hoebee; Carel Thijs; Dirkje S. Postma; Tjeerd G. Kimman; Foekje F. Stelma

doi:10.1128/CVI.00175-07

Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study

Sander Banus
, Renske W B Bottema
, Christine L E Siezen
, Rob J. Vandebriel
, Johan Reimerink
, Monique Mommers
, Gerard H. Koppelman
, Barbara Hoebee
, Carel Thijs
, Dirkje S. Postma
, Tjeerd G. Kimman^*
, Foekje F. Stelma

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

Abstract

We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of rs2770150, supporting a role for Toll-like receptor 4 in the antibody response to wP vaccination.

Original language	English
Pages (from-to)	1377-1380
Number of pages	4
Journal	Clinical and Vaccine Immunology
Volume	14
Issue number	10
DOIs	https://doi.org/10.1128/CVI.00175-07
Publication status	Published - Oct 2007
Externally published	Yes

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10.1128/CVI.00175-07

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Banus, S., Bottema, R. W. B., Siezen, C. L. E., Vandebriel, R. J., Reimerink, J., Mommers, M., Koppelman, G. H., Hoebee, B., Thijs, C., Postma, D. S., Kimman, T. G., & Stelma, F. F. (2007). Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study. Clinical and Vaccine Immunology, 14(10), 1377-1380. https://doi.org/10.1128/CVI.00175-07

@article{21560216a63b436887c908c9e1fd6435,

title = "Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study",

abstract = "We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of rs2770150, supporting a role for Toll-like receptor 4 in the antibody response to wP vaccination.",

author = "Sander Banus and Bottema, \{Renske W B\} and Siezen, \{Christine L E\} and Vandebriel, \{Rob J.\} and Johan Reimerink and Monique Mommers and Koppelman, \{Gerard H.\} and Barbara Hoebee and Carel Thijs and Postma, \{Dirkje S.\} and Kimman, \{Tjeerd G.\} and Stelma, \{Foekje F.\}",

year = "2007",

month = oct,

doi = "10.1128/CVI.00175-07",

language = "English",

volume = "14",

pages = "1377--1380",

journal = "Clinical and Vaccine Immunology",

issn = "1556-6811",

publisher = "American Society for Microbiology",

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}

Banus, S, Bottema, RWB, Siezen, CLE, Vandebriel, RJ, Reimerink, J, Mommers, M, Koppelman, GH, Hoebee, B, Thijs, C, Postma, DS, Kimman, TG & Stelma, FF 2007, 'Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study', Clinical and Vaccine Immunology, vol. 14, no. 10, pp. 1377-1380. https://doi.org/10.1128/CVI.00175-07

TY - JOUR

T1 - Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study

AU - Banus, Sander

AU - Bottema, Renske W B

AU - Siezen, Christine L E

AU - Vandebriel, Rob J.

AU - Reimerink, Johan

AU - Mommers, Monique

AU - Koppelman, Gerard H.

AU - Hoebee, Barbara

AU - Thijs, Carel

AU - Postma, Dirkje S.

AU - Kimman, Tjeerd G.

AU - Stelma, Foekje F.

PY - 2007/10

Y1 - 2007/10

N2 - We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of rs2770150, supporting a role for Toll-like receptor 4 in the antibody response to wP vaccination.

AB - We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of rs2770150, supporting a role for Toll-like receptor 4 in the antibody response to wP vaccination.

UR - https://www.scopus.com/pages/publications/35548944489

U2 - 10.1128/CVI.00175-07

DO - 10.1128/CVI.00175-07

M3 - Article

C2 - 17699831

AN - SCOPUS:35548944489

SN - 1556-6811

VL - 14

SP - 1377

EP - 1380

JO - Clinical and Vaccine Immunology

JF - Clinical and Vaccine Immunology

IS - 10

ER -

Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study

Abstract

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