Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study

Sander Banus; Renske W B Bottema; Christine L E Siezen; Rob J. Vandebriel; Johan Reimerink; Monique Mommers; Gerard H. Koppelman; Barbara Hoebee; Carel Thijs; Dirkje S. Postma; Tjeerd G. Kimman; Foekje F. Stelma

doi:10.1128/CVI.00175-07

Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study

Sander Banus, Renske W B Bottema, Christine L E Siezen, Rob J. Vandebriel, Johan Reimerink, Monique Mommers, Gerard H. Koppelman, Barbara Hoebee, Carel Thijs, Dirkje S. Postma, Tjeerd G. Kimman^*, Foekje F. Stelma

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

Abstract

We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of rs2770150, supporting a role for Toll-like receptor 4 in the antibody response to wP vaccination.

Original language	English
Pages (from-to)	1377-1380
Number of pages	4
Journal	Clinical and Vaccine Immunology
Volume	14
Issue number	10
DOIs	https://doi.org/10.1128/CVI.00175-07
Publication status	Published - Oct 2007
Externally published	Yes

Access to Document

10.1128/CVI.00175-07

Cite this

Banus, S., Bottema, R. W. B., Siezen, C. L. E., Vandebriel, R. J., Reimerink, J., Mommers, M., Koppelman, G. H., Hoebee, B., Thijs, C., Postma, D. S., Kimman, T. G., & Stelma, F. F. (2007). Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study. Clinical and Vaccine Immunology, 14(10), 1377-1380. https://doi.org/10.1128/CVI.00175-07

@article{21560216a63b436887c908c9e1fd6435,

title = "Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study",

abstract = "We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of rs2770150, supporting a role for Toll-like receptor 4 in the antibody response to wP vaccination.",

author = "Sander Banus and Bottema, {Renske W B} and Siezen, {Christine L E} and Vandebriel, {Rob J.} and Johan Reimerink and Monique Mommers and Koppelman, {Gerard H.} and Barbara Hoebee and Carel Thijs and Postma, {Dirkje S.} and Kimman, {Tjeerd G.} and Stelma, {Foekje F.}",

year = "2007",

month = oct,

doi = "10.1128/CVI.00175-07",

language = "English",

volume = "14",

pages = "1377--1380",

journal = "Clinical and Vaccine Immunology",

issn = "1556-6811",

publisher = "American Society for Microbiology",

number = "10",

}

Banus, S, Bottema, RWB, Siezen, CLE, Vandebriel, RJ, Reimerink, J, Mommers, M, Koppelman, GH, Hoebee, B, Thijs, C, Postma, DS, Kimman, TG & Stelma, FF 2007, 'Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study', Clinical and Vaccine Immunology, vol. 14, no. 10, pp. 1377-1380. https://doi.org/10.1128/CVI.00175-07

TY - JOUR

T1 - Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study

AU - Banus, Sander

AU - Bottema, Renske W B

AU - Siezen, Christine L E

AU - Vandebriel, Rob J.

AU - Reimerink, Johan

AU - Mommers, Monique

AU - Koppelman, Gerard H.

AU - Hoebee, Barbara

AU - Thijs, Carel

AU - Postma, Dirkje S.

AU - Kimman, Tjeerd G.

AU - Stelma, Foekje F.

PY - 2007/10

Y1 - 2007/10

N2 - We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of rs2770150, supporting a role for Toll-like receptor 4 in the antibody response to wP vaccination.

AB - We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of rs2770150, supporting a role for Toll-like receptor 4 in the antibody response to wP vaccination.

UR - http://www.scopus.com/inward/record.url?scp=35548944489&partnerID=8YFLogxK

U2 - 10.1128/CVI.00175-07

DO - 10.1128/CVI.00175-07

M3 - Article

C2 - 17699831

AN - SCOPUS:35548944489

SN - 1556-6811

VL - 14

SP - 1377

EP - 1380

JO - Clinical and Vaccine Immunology

JF - Clinical and Vaccine Immunology

IS - 10

ER -

Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study

Abstract

Access to Document

Other files and links

Fingerprint

Cite this