Therapy Failure following Selection of Enfuvirtide-Resistant HIV-1 in Cerebrospinal Fluid

S.F.L. van Lelyveld; M.J.G. Nijhuis; F Baatz; I. Wilting; W.M. van den Bergh; M Kurowski; D. de Jong; A.I.M. Hoepelman; A.M.J. Wensing

Therapy Failure following Selection of Enfuvirtide-Resistant HIV-1 in Cerebrospinal Fluid

S.F.L. van Lelyveld, M.J.G. Nijhuis, F Baatz, I. Wilting, W.M. van den Bergh, M Kurowski, D. de Jong, A.I.M. Hoepelman, A.M.J. Wensing

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We report the selection of enfuvirtide-resistant human immunodeficiency virus type 1 in cerebrospinal fluid, resulting in subsequent loss of viral suppression in the plasma. This case report emphasizes the potential danger of low-level penetration of entry inhibitors into the central nervous system.

Original language	English
Pages (from-to)	387-390
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	50
Issue number	3
Publication status	Published - 1 Feb 2010

Keywords

BLOOD

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http://www.ncbi.nlm.nih.gov/pubmed/20047481

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title = "Therapy Failure following Selection of Enfuvirtide-Resistant HIV-1 in Cerebrospinal Fluid",

abstract = "We report the selection of enfuvirtide-resistant human immunodeficiency virus type 1 in cerebrospinal fluid, resulting in subsequent loss of viral suppression in the plasma. This case report emphasizes the potential danger of low-level penetration of entry inhibitors into the central nervous system.",

keywords = "BLOOD",

author = "\{van Lelyveld\}, S.F.L. and M.J.G. Nijhuis and F Baatz and I. Wilting and \{van den Bergh\}, W.M. and M Kurowski and \{de Jong\}, D. and A.I.M. Hoepelman and A.M.J. Wensing",

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AU - van Lelyveld, S.F.L.

AU - Nijhuis, M.J.G.

AU - Baatz, F

AU - Wilting, I.

AU - van den Bergh, W.M.

AU - Kurowski, M

AU - de Jong, D.

AU - Hoepelman, A.I.M.

AU - Wensing, A.M.J.

PY - 2010/2/1

Y1 - 2010/2/1

N2 - We report the selection of enfuvirtide-resistant human immunodeficiency virus type 1 in cerebrospinal fluid, resulting in subsequent loss of viral suppression in the plasma. This case report emphasizes the potential danger of low-level penetration of entry inhibitors into the central nervous system.

AB - We report the selection of enfuvirtide-resistant human immunodeficiency virus type 1 in cerebrospinal fluid, resulting in subsequent loss of viral suppression in the plasma. This case report emphasizes the potential danger of low-level penetration of entry inhibitors into the central nervous system.

KW - BLOOD

M3 - Article

SN - 1058-4838

VL - 50

SP - 387

EP - 390

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 3

ER -

Therapy Failure following Selection of Enfuvirtide-Resistant HIV-1 in Cerebrospinal Fluid

Abstract

Keywords

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