TY - JOUR
T1 - The value of yttrium-90 PET/CT after hepatic radioembolization
T2 - a pictorial essay
AU - Alsultan, Ahmed A.
AU - Smits, Maarten L.J.
AU - Barentsz, Maarten W.
AU - Braat, Arthur J.A.T.
AU - Lam, Marnix G.E.H.
PY - 2019/8/1
Y1 - 2019/8/1
N2 - Introduction: Distribution of microspheres after radioembolization can be accurately visualized using PET/CT. In this pictorial essay, we aim to demonstrate the value of 90Y-PET/CT after radioembolization. Methods: 90Y-PET/CT imaging was routinely performed after radioembolization at our institute. Patients were scanned the same day or the day after treatment, using a scanner with time-of-flight technology. We retrospectively reviewed all 90Y-PET/CTs from patients treated with radioembolization (both glass and resin microspheres) between January 2011 and January 2019. Five cases were selected that are illustrative of the added value of PET/CT after radioembolization. Results: 90Y-PET/CT allows for distribution assessment and dosimetry of 90Y-microspheres. It was used for the assessment of treatment success by visualization of tumor targeting, quantification of the absorbed dose, prediction of complications such as radioembolization-induced liver disease, and determining the required dosage for retreatment. Conclusion: PET/CT is an excellent modality for post-treatment imaging of 90Y-microspheres and could lead to improved dose planning and more personalized treatment.
AB - Introduction: Distribution of microspheres after radioembolization can be accurately visualized using PET/CT. In this pictorial essay, we aim to demonstrate the value of 90Y-PET/CT after radioembolization. Methods: 90Y-PET/CT imaging was routinely performed after radioembolization at our institute. Patients were scanned the same day or the day after treatment, using a scanner with time-of-flight technology. We retrospectively reviewed all 90Y-PET/CTs from patients treated with radioembolization (both glass and resin microspheres) between January 2011 and January 2019. Five cases were selected that are illustrative of the added value of PET/CT after radioembolization. Results: 90Y-PET/CT allows for distribution assessment and dosimetry of 90Y-microspheres. It was used for the assessment of treatment success by visualization of tumor targeting, quantification of the absorbed dose, prediction of complications such as radioembolization-induced liver disease, and determining the required dosage for retreatment. Conclusion: PET/CT is an excellent modality for post-treatment imaging of 90Y-microspheres and could lead to improved dose planning and more personalized treatment.
KW - Y-microspheres
KW - Y-PET/CT
KW - Intra-arterial radioembolization
KW - Post-treatment imaging
KW - CT
KW - Y-90-PET
KW - Y-90-microspheres
UR - http://www.scopus.com/inward/record.url?scp=85069495637&partnerID=8YFLogxK
U2 - 10.1007/s40336-019-00335-2
DO - 10.1007/s40336-019-00335-2
M3 - Article
AN - SCOPUS:85069495637
SN - 2281-5872
VL - 7
SP - 303
EP - 312
JO - Clinical and translational imaging
JF - Clinical and translational imaging
IS - 4
ER -