The Use of MR-Guided Radiation Therapy for Pancreatic Cancer

Lois A. Daamen; Parag J. Parikh; William A. Hall

doi:10.1016/j.semradonc.2023.10.002

The Use of MR-Guided Radiation Therapy for Pancreatic Cancer

Lois A. Daamen, Parag J. Parikh, William A. Hall^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

Abstract

The introduction of online adaptive magnetic resonance (MR)-guided radiation therapy (RT) has enabled safe treatment of pancreatic cancer with ablative doses. The aim of this review is to provide a comprehensive overview of the current literature on the use and clinical outcomes of MR-guided RT for treatment of pancreatic cancer. Relevant outcomes included toxicity, tumor response, survival and quality of life. The results of these studies support further investigation of the effectiveness of ablative MR-guided SBRT as a low-toxic, minimally-invasive therapy for localized pancreatic cancer in prospective clinical trials.

Original language	English
Pages (from-to)	23-35
Number of pages	13
Journal	Seminars in Radiation Oncology
Volume	34
Issue number	1
DOIs	https://doi.org/10.1016/j.semradonc.2023.10.002
Publication status	Published - Jan 2024

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10.1016/j.semradonc.2023.10.002

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title = "The Use of MR-Guided Radiation Therapy for Pancreatic Cancer",

abstract = "The introduction of online adaptive magnetic resonance (MR)-guided radiation therapy (RT) has enabled safe treatment of pancreatic cancer with ablative doses. The aim of this review is to provide a comprehensive overview of the current literature on the use and clinical outcomes of MR-guided RT for treatment of pancreatic cancer. Relevant outcomes included toxicity, tumor response, survival and quality of life. The results of these studies support further investigation of the effectiveness of ablative MR-guided SBRT as a low-toxic, minimally-invasive therapy for localized pancreatic cancer in prospective clinical trials.",

author = "Daamen, {Lois A.} and Parikh, {Parag J.} and Hall, {William A.}",

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year = "2024",

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N2 - The introduction of online adaptive magnetic resonance (MR)-guided radiation therapy (RT) has enabled safe treatment of pancreatic cancer with ablative doses. The aim of this review is to provide a comprehensive overview of the current literature on the use and clinical outcomes of MR-guided RT for treatment of pancreatic cancer. Relevant outcomes included toxicity, tumor response, survival and quality of life. The results of these studies support further investigation of the effectiveness of ablative MR-guided SBRT as a low-toxic, minimally-invasive therapy for localized pancreatic cancer in prospective clinical trials.

AB - The introduction of online adaptive magnetic resonance (MR)-guided radiation therapy (RT) has enabled safe treatment of pancreatic cancer with ablative doses. The aim of this review is to provide a comprehensive overview of the current literature on the use and clinical outcomes of MR-guided RT for treatment of pancreatic cancer. Relevant outcomes included toxicity, tumor response, survival and quality of life. The results of these studies support further investigation of the effectiveness of ablative MR-guided SBRT as a low-toxic, minimally-invasive therapy for localized pancreatic cancer in prospective clinical trials.

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The Use of MR-Guided Radiation Therapy for Pancreatic Cancer

Abstract

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