The Upper Hand of the Otu Amyloid Fibers: Increasing Enzymatic Activity and Prolonging Lifespan

Catherine Rabouille

doi:10.1016/j.molcel.2019.03.038

The Upper Hand of the Otu Amyloid Fibers: Increasing Enzymatic Activity and Prolonging Lifespan

Catherine Rabouille^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

Abstract

The formation of amyloid fibers is usually associated with aging and neurodegeneration. In this issue of Molecular Cell, Ji et al. (2019) demonstrate that the deubiquitinase Otu coalesces into amyloid-like fibers to enhance its activity and ensure its optimum biological function.

Original language	English
Pages (from-to)	225-226
Number of pages	2
Journal	Molecular Cell
Volume	74
Issue number	2
DOIs	https://doi.org/10.1016/j.molcel.2019.03.038
Publication status	Published - 18 Apr 2019

Keywords

Animals
Basic Helix-Loop-Helix Transcription Factors
Drosophila
Drosophila Proteins
Longevity

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10.1016/j.molcel.2019.03.038

rabouilleFinal published version, 213 KBLicence: Taverne

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title = "The Upper Hand of the Otu Amyloid Fibers: Increasing Enzymatic Activity and Prolonging Lifespan",

abstract = "The formation of amyloid fibers is usually associated with aging and neurodegeneration. In this issue of Molecular Cell, Ji et al. (2019) demonstrate that the deubiquitinase Otu coalesces into amyloid-like fibers to enhance its activity and ensure its optimum biological function.",

keywords = "Animals, Basic Helix-Loop-Helix Transcription Factors, Drosophila, Drosophila Proteins, Longevity",

author = "Catherine Rabouille",

year = "2019",

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N2 - The formation of amyloid fibers is usually associated with aging and neurodegeneration. In this issue of Molecular Cell, Ji et al. (2019) demonstrate that the deubiquitinase Otu coalesces into amyloid-like fibers to enhance its activity and ensure its optimum biological function.

AB - The formation of amyloid fibers is usually associated with aging and neurodegeneration. In this issue of Molecular Cell, Ji et al. (2019) demonstrate that the deubiquitinase Otu coalesces into amyloid-like fibers to enhance its activity and ensure its optimum biological function.

KW - Animals

KW - Basic Helix-Loop-Helix Transcription Factors

KW - Drosophila

KW - Drosophila Proteins

KW - Longevity

UR - https://www.scopus.com/pages/publications/85063682270

U2 - 10.1016/j.molcel.2019.03.038

DO - 10.1016/j.molcel.2019.03.038

M3 - Short survey

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AN - SCOPUS:85063682270

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JO - Molecular Cell

JF - Molecular Cell

IS - 2

ER -

The Upper Hand of the Otu Amyloid Fibers: Increasing Enzymatic Activity and Prolonging Lifespan

Abstract

Keywords

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