The Rise of Adaptive Platform Trials in Critical Care

LP Derde

doi:10.1164/rccm.202401-0101CP

The Rise of Adaptive Platform Trials in Critical Care

, LP Derde

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

As durable learning research systems, adaptive platform trials represent a transformative new approach to accelerating clinical evaluation and discovery in critical care. This Perspective provides a brief introduction to the concept of adaptive platform trials, describes several established and emerging platforms in critical care, and surveys some opportunities and challenges for their implementation and impact.

Original language	English
Pages (from-to)	491-496
Number of pages	6
Journal	American journal of respiratory and critical care medicine
Volume	209
Issue number	5
DOIs	https://doi.org/10.1164/rccm.202401-0101CP
Publication status	Published - 1 Mar 2024

Keywords

Critical Care
Humans

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10.1164/rccm.202401-0101CPLicence: CC BY

bos-et-al-2024-the-rise-of-adaptive-platform-trials-in-critical-careFinal published version, 549 KBLicence: CC BY

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AB - As durable learning research systems, adaptive platform trials represent a transformative new approach to accelerating clinical evaluation and discovery in critical care. This Perspective provides a brief introduction to the concept of adaptive platform trials, describes several established and emerging platforms in critical care, and surveys some opportunities and challenges for their implementation and impact.

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The Rise of Adaptive Platform Trials in Critical Care

Abstract

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