The perinatal ontogeny of estrogen receptor-immunoreactivity in the developing male and female rat hypothalamus

R. Jeroen Pasterkamp; Kazunari Yuri; David T.M. Visser; Shinji Hayashi; Mitsuhiro Kawata

doi:10.1016/0165-3806(95)00185-9

The perinatal ontogeny of estrogen receptor-immunoreactivity in the developing male and female rat hypothalamus

R. Jeroen Pasterkamp^*
, Kazunari Yuri
, David T.M. Visser
, Shinji Hayashi
, Mitsuhiro Kawata

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

19 Citations (Scopus)

Abstract

Developmental expression of the estrogen receptor (ER) in rat hypothalamus was examined using immunohistochemistry. In the medial preoptic nucleus and ventromedial nucleus ER-immunoreactivity was detected as early as E17, whereas ER protein expression in the periventricular preoptic nucleus and arcuate nucleus was delayed until E19. These results show that following a region specific onset of the ER protein expression sex differences in ER levels are already detectable during the perinatal period.

Original language	English
Pages (from-to)	300-303
Number of pages	4
Journal	Developmental Brain Research
Volume	91
Issue number	2
DOIs	https://doi.org/10.1016/0165-3806(95)00185-9
Publication status	Published - 26 Feb 1996

Keywords

Estrogen receptor
Hypothalamus
Immunohistochemistry
Perinatal development
Rat
Sexual differentiation

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10.1016/0165-3806(95)00185-9

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abstract = "Developmental expression of the estrogen receptor (ER) in rat hypothalamus was examined using immunohistochemistry. In the medial preoptic nucleus and ventromedial nucleus ER-immunoreactivity was detected as early as E17, whereas ER protein expression in the periventricular preoptic nucleus and arcuate nucleus was delayed until E19. These results show that following a region specific onset of the ER protein expression sex differences in ER levels are already detectable during the perinatal period.",

keywords = "Estrogen receptor, Hypothalamus, Immunohistochemistry, Perinatal development, Rat, Sexual differentiation",

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AU - Pasterkamp, R. Jeroen

AU - Yuri, Kazunari

AU - Visser, David T.M.

AU - Hayashi, Shinji

AU - Kawata, Mitsuhiro

PY - 1996/2/26

Y1 - 1996/2/26

N2 - Developmental expression of the estrogen receptor (ER) in rat hypothalamus was examined using immunohistochemistry. In the medial preoptic nucleus and ventromedial nucleus ER-immunoreactivity was detected as early as E17, whereas ER protein expression in the periventricular preoptic nucleus and arcuate nucleus was delayed until E19. These results show that following a region specific onset of the ER protein expression sex differences in ER levels are already detectable during the perinatal period.

AB - Developmental expression of the estrogen receptor (ER) in rat hypothalamus was examined using immunohistochemistry. In the medial preoptic nucleus and ventromedial nucleus ER-immunoreactivity was detected as early as E17, whereas ER protein expression in the periventricular preoptic nucleus and arcuate nucleus was delayed until E19. These results show that following a region specific onset of the ER protein expression sex differences in ER levels are already detectable during the perinatal period.

KW - Estrogen receptor

KW - Hypothalamus

KW - Immunohistochemistry

KW - Perinatal development

KW - Rat

KW - Sexual differentiation

UR - https://www.scopus.com/pages/publications/0030058176

U2 - 10.1016/0165-3806(95)00185-9

DO - 10.1016/0165-3806(95)00185-9

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SN - 0165-3806

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EP - 303

JO - Developmental Brain Research

JF - Developmental Brain Research

IS - 2

ER -

The perinatal ontogeny of estrogen receptor-immunoreactivity in the developing male and female rat hypothalamus

Abstract

Keywords

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