TY - JOUR
T1 - The perinatal ontogeny of estrogen receptor-immunoreactivity in the developing male and female rat hypothalamus
AU - Pasterkamp, R. Jeroen
AU - Yuri, Kazunari
AU - Visser, David T.M.
AU - Hayashi, Shinji
AU - Kawata, Mitsuhiro
PY - 1996/2/26
Y1 - 1996/2/26
N2 - Developmental expression of the estrogen receptor (ER) in rat hypothalamus was examined using immunohistochemistry. In the medial preoptic nucleus and ventromedial nucleus ER-immunoreactivity was detected as early as E17, whereas ER protein expression in the periventricular preoptic nucleus and arcuate nucleus was delayed until E19. These results show that following a region specific onset of the ER protein expression sex differences in ER levels are already detectable during the perinatal period.
AB - Developmental expression of the estrogen receptor (ER) in rat hypothalamus was examined using immunohistochemistry. In the medial preoptic nucleus and ventromedial nucleus ER-immunoreactivity was detected as early as E17, whereas ER protein expression in the periventricular preoptic nucleus and arcuate nucleus was delayed until E19. These results show that following a region specific onset of the ER protein expression sex differences in ER levels are already detectable during the perinatal period.
KW - Estrogen receptor
KW - Hypothalamus
KW - Immunohistochemistry
KW - Perinatal development
KW - Rat
KW - Sexual differentiation
UR - http://www.scopus.com/inward/record.url?scp=0030058176&partnerID=8YFLogxK
U2 - 10.1016/0165-3806(95)00185-9
DO - 10.1016/0165-3806(95)00185-9
M3 - Article
C2 - 8852382
AN - SCOPUS:0030058176
SN - 0165-3806
VL - 91
SP - 300
EP - 303
JO - Developmental Brain Research
JF - Developmental Brain Research
IS - 2
ER -