The Kraepelinian dichotomy: Evidence from developmental and neuroimaging studies

V. A. Curtis*, J. Van Os, R. M. Murray

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

17 Citations (Scopus)

Abstract

Schizophrenia and affective disorder are both characterized by disturbances of thought, behavior, and mood, but for much of the century since Kraepelin(I) distinguished the two, investigators approached them as distinct disorders with quite separate etiologies. However, dissatisfaction with the Kraepelinian dichotomy has been growing,(2-4) and recent evidence from developmental, genetic, epidemiological, and outcome studies suggests that the two have much more in common than was previously thought.

Original languageEnglish
Pages (from-to)398-405
Number of pages8
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume12
Issue number3
DOIs
Publication statusPublished - 2000
Externally publishedYes

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