The importance of animal specificity in animal experimentation, part I: Anatomy in relation to pediatric urology

Magdalena Fossum; Martin Kaefer; Darius Bagli; Luke Harper; Katherine W. Herbst; Caleb P. Nelson; Luis H. Braga; Anka Nieuwhof-Leppink; Nicolas Kalfa; Massimo Garriboli; Salvatore Cascio

doi:10.1016/j.jpurol.2023.12.006

The importance of animal specificity in animal experimentation, part I: Anatomy in relation to pediatric urology

Magdalena Fossum^*, Martin Kaefer, Darius Bagli, Luke Harper, Katherine W. Herbst, Caleb P. Nelson, Luis H. Braga, Anka Nieuwhof-Leppink, Nicolas Kalfa, Massimo Garriboli, Salvatore Cascio,

^*Corresponding author for this work

Incontinence team

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Why and when is animal experimentation relevant? The answer to this question depends on the research question. In this short educational article we aim to raise awareness of the importance of formulating a very specific research question before choosing an animal species. An awareness of anatomical and physiological differences vis-a-vis similarities between species, will increase the potential for obtaining data that is relevant for translation to human conditions.

Original language	English
Pages (from-to)	312-314
Number of pages	3
Journal	Journal of Pediatric Urology
Volume	20
Issue number	2
DOIs	https://doi.org/10.1016/j.jpurol.2023.12.006
Publication status	Published - Apr 2024

Keywords

Anatomy
Animal Research
Ethics
Guidelines
Pediatric urology

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10.1016/j.jpurol.2023.12.006

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abstract = "Why and when is animal experimentation relevant? The answer to this question depends on the research question. In this short educational article we aim to raise awareness of the importance of formulating a very specific research question before choosing an animal species. An awareness of anatomical and physiological differences vis-a-vis similarities between species, will increase the potential for obtaining data that is relevant for translation to human conditions.",

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doi = "10.1016/j.jpurol.2023.12.006",

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AU - Fossum, Magdalena

AU - Kaefer, Martin

AU - Bagli, Darius

AU - Harper, Luke

AU - Herbst, Katherine W.

AU - Nelson, Caleb P.

AU - Braga, Luis H.

AU - Nieuwhof-Leppink, Anka

AU - Kalfa, Nicolas

AU - Garriboli, Massimo

AU - Cascio, Salvatore

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KW - Animal Research

KW - Ethics

KW - Guidelines

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ER -

The importance of animal specificity in animal experimentation, part I: Anatomy in relation to pediatric urology

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