The impact and management of hyperemesis gravidarum: Current and future perspectives

Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy affecting around 1%–3% of pregnancies worldwide and is the most common reason for hospital admission in early pregnancy. HG can have lasting consequences for both pregnant individuals and their offspring. Current best-practice management includes symptomatic treatment with anti-emetic pharmacological treatment, rehydration if needed, and psychological support. There is a lack of high-quality evidence on treatment for HG. Future research should focus on understanding the cause, developing effective treatment, and so limiting the burden of disease on patients and healthcare systems.