The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation

Robbert Van Der Voort; Taher E.I. Taher; Patrick W.B. Derksen; Marcel Spaargaren; Ronald Van Der Neut; Steven T. Pals

doi:10.1016/s0065-230x(00)79002-6

The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation

Robbert Van Der Voort
, Taher E.I. Taher
, Patrick W.B. Derksen
, Marcel Spaargaren
, Ronald Van Der Neut
, Steven T. Pals

Research output: Contribution to journal › Review article › peer-review

95 Citations (Scopus)

Abstract

This article summarizes the structure, signal transduction and physiologic functions of the HGF/Met pathway, as well as its role in tumor growth, invasion, and metastasis. Moreover, it highlights recent studies indicating a role for the HGF/Met pathway in antigen-specific B-cell development and B-cell neoplasia.

Original language	English
Pages (from-to)	39-90
Number of pages	52
Journal	Advances in Cancer Research
Volume	79
DOIs	https://doi.org/10.1016/s0065-230x(00)79002-6
Publication status	Published - 2000
Externally published	Yes

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10.1016/s0065-230x(00)79002-6

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title = "The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation",

abstract = "This article summarizes the structure, signal transduction and physiologic functions of the HGF/Met pathway, as well as its role in tumor growth, invasion, and metastasis. Moreover, it highlights recent studies indicating a role for the HGF/Met pathway in antigen-specific B-cell development and B-cell neoplasia.",

author = "\{Van Der Voort\}, Robbert and Taher, \{Taher E.I.\} and Derksen, \{Patrick W.B.\} and Marcel Spaargaren and \{Van Der Neut\}, Ronald and Pals, \{Steven T.\}",

note = "Funding Information: This study was financially supported by the Dutch Cancer Society (KWF), the Association for International Cancer Research (AICR), and the University of Amsterdam.",

year = "2000",

doi = "10.1016/s0065-230x(00)79002-6",

language = "English",

volume = "79",

pages = "39--90",

journal = "Advances in Cancer Research",

issn = "0065-230X",

publisher = "Academic Press Inc.",

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T1 - The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation

AU - Van Der Voort, Robbert

AU - Taher, Taher E.I.

AU - Derksen, Patrick W.B.

AU - Spaargaren, Marcel

AU - Van Der Neut, Ronald

AU - Pals, Steven T.

N1 - Funding Information: This study was financially supported by the Dutch Cancer Society (KWF), the Association for International Cancer Research (AICR), and the University of Amsterdam.

PY - 2000

Y1 - 2000

N2 - This article summarizes the structure, signal transduction and physiologic functions of the HGF/Met pathway, as well as its role in tumor growth, invasion, and metastasis. Moreover, it highlights recent studies indicating a role for the HGF/Met pathway in antigen-specific B-cell development and B-cell neoplasia.

AB - This article summarizes the structure, signal transduction and physiologic functions of the HGF/Met pathway, as well as its role in tumor growth, invasion, and metastasis. Moreover, it highlights recent studies indicating a role for the HGF/Met pathway in antigen-specific B-cell development and B-cell neoplasia.

UR - https://www.scopus.com/pages/publications/0034006675

U2 - 10.1016/s0065-230x(00)79002-6

DO - 10.1016/s0065-230x(00)79002-6

M3 - Review article

C2 - 10818677

AN - SCOPUS:0034006675

SN - 0065-230X

VL - 79

SP - 39

EP - 90

JO - Advances in Cancer Research

JF - Advances in Cancer Research

ER -

The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation

Abstract

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