TY - JOUR
T1 - The diagnostic value of magnetic resonance imaging in differentiating benign and malignant pediatric ovarian tumors
AU - Janssen, Carlijn L.
AU - Littooij, Annemieke S.
AU - Fiocco, Marta
AU - Huige, Josephine C.B.
AU - de Krijger, Ronald R.
AU - Hulsker, Caroline C.C.
AU - Goverde, Angelique J.
AU - Zsiros, József
AU - Mavinkurve-Groothuis, Annelies M.C.
N1 - Publisher Copyright:
© 2020, The Author(s).
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/3
Y1 - 2021/3
N2 - BACKGROUND: The diagnostic workup of ovarian tumors in children and adolescents is challenging because preserving fertility, in addition to oncological safety, is of particular importance in this population. Therefore, a thorough preoperative assessment of ovarian tumors is required.OBJECTIVE: To investigate the diagnostic value of MR imaging in differentiating benign from malignant ovarian tumors in children and adolescents.MATERIALS AND METHODS: We conducted a retrospective study of all children and adolescents age <18 years who underwent MR imaging of ovarian tumors during 2014-2019 at a pediatric specialty center. Two radiologists reviewed all MR imaging. We used pathology reports to define the histological diagnosis.RESULTS: We included 30 girls who underwent MR imaging for an ovarian tumor. Signs indicative for malignancy were tumors with a diameter ≥8 cm, with areas of contrast enhancement, irregular margins, extracapsular tumor growth, and ascites. All benign and malignant ovarian tumors were correctly identified by the radiologists.CONCLUSION: The diagnostic utility of MR imaging in classifying ovarian tumors in children and adolescents as benign or malignant is promising and might aid in defining the indication for ovarian-sparing versus non-ovarian-sparing surgery. We recommend evaluating these tumors with MR imaging prior to deciding on surgical treatment.
AB - BACKGROUND: The diagnostic workup of ovarian tumors in children and adolescents is challenging because preserving fertility, in addition to oncological safety, is of particular importance in this population. Therefore, a thorough preoperative assessment of ovarian tumors is required.OBJECTIVE: To investigate the diagnostic value of MR imaging in differentiating benign from malignant ovarian tumors in children and adolescents.MATERIALS AND METHODS: We conducted a retrospective study of all children and adolescents age <18 years who underwent MR imaging of ovarian tumors during 2014-2019 at a pediatric specialty center. Two radiologists reviewed all MR imaging. We used pathology reports to define the histological diagnosis.RESULTS: We included 30 girls who underwent MR imaging for an ovarian tumor. Signs indicative for malignancy were tumors with a diameter ≥8 cm, with areas of contrast enhancement, irregular margins, extracapsular tumor growth, and ascites. All benign and malignant ovarian tumors were correctly identified by the radiologists.CONCLUSION: The diagnostic utility of MR imaging in classifying ovarian tumors in children and adolescents as benign or malignant is promising and might aid in defining the indication for ovarian-sparing versus non-ovarian-sparing surgery. We recommend evaluating these tumors with MR imaging prior to deciding on surgical treatment.
KW - Benign
KW - Children
KW - Magnetic resonance imaging
KW - Malignant
KW - Ovarian preservation
KW - Ovaries
KW - Tumor
UR - http://www.scopus.com/inward/record.url?scp=85096025786&partnerID=8YFLogxK
U2 - 10.1007/s00247-020-04871-2
DO - 10.1007/s00247-020-04871-2
M3 - Article
C2 - 33185738
AN - SCOPUS:85096025786
SN - 0301-0449
VL - 51
SP - 427
EP - 434
JO - Pediatric Radiology
JF - Pediatric Radiology
IS - 3
ER -