The clinical utility of basophil activation testing in diagnosis and monitoring of allergic disease

H. J. Hoffmann*, A. F. Santos, C. Mayorga, A. Nopp, B. Eberlein, M. Ferrer, P. Rouzaire, D. G. Ebo, V. Sabato, M. L. Sanz, T. Pecaric-Petkovic, S. U. Patil, O. V. Hausmann, W. G. Shreffler, P. Korosec, E. F. Knol

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

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    Abstract

    The basophil activation test (BAT) has become a pervasive test for allergic response through the development of flow cytometry, discovery of activation markers such as CD63 and unique markers identifying basophil granulocytes. Basophil activation test measures basophil response to allergen cross-linking IgE on between 150 and 2000 basophil granulocytes in

    Original languageEnglish
    Pages (from-to)1393-1405
    Number of pages13
    JournalAllergy
    Volume70
    Issue number11
    DOIs
    Publication statusPublished - 1 Nov 2015

    Keywords

    • allergy diagnosis
    • allergy monitoring
    • basophil activation test
    • basophil granulocyte
    • CD63

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