The association between patient satisfaction with information and adherence to oral anticancer agents

Eward J Melis, Jeannette Ef Zwart-van Rijkom, Toine Cg Egberts, Bart Jf van den Bemt, Petronella O Witteveen, Helga Gardarsdottir*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

INTRODUCTION: Adherence to anticancer agents is a critical factor in achieving adequate clinical response, and became a major challenge for patients and caregivers since the increased substitution of parenteral cytostatic by oral drugs. One of the factors that influences adherence is how well informed patients are about their therapy. This study assesses the association between patient satisfaction with information about oral anticancer agents and adherence.

MATERIALS AND METHODS: This study was conducted among patients (≥18 years) who began oral anticancer therapy. Patients satisfaction with information and adherence were assessed using validated questionnaires. Adherence was also assessed using refill data. Logistic regression was applied to assess the association between overall patient satisfaction with information and both self-reported adherence and adherence based on an MPR value of above 80%.

RESULTS: In total, 124 patients were included in the study. The median (IQR) satisfaction with information was 15.0(4) on a scale of 0-17. Eighty-two percent of participants reported adherence, while the refill data demonstrated that 64.5% of patients had an adherence rate of 80% or higher. Overall satisfaction with information was not significantly associated with self-reported adherence (OR adj 0.98 [95% CI 0.85-1.15]) or refill-based adherence (OR adj 1.11 [95% CI 0.99-1.24]).

CONCLUSION: The findings indicate no significant relationship between patient satisfaction with information and adherence. The population was highly satisfied with information about the oral anticancer agents, which indicates a high level of satisfaction with usual care. However, the refill data reveals that 35.5% of patients were not adherent.

Original languageEnglish
Pages (from-to)637-645
Number of pages9
JournalJournal of Oncology Pharmacy Practice
Volume29
Issue number3
Early online date7 Feb 2022
DOIs
Publication statusPublished - Apr 2023

Keywords

  • adherence
  • cancer
  • Oral anticancer agent
  • oral anticancer therapy
  • satisfaction with information

Fingerprint

Dive into the research topics of 'The association between patient satisfaction with information and adherence to oral anticancer agents'. Together they form a unique fingerprint.

Cite this