The association between medication use and health-related quality of life in multimorbid older patients with polypharmacy

Charlotte Falke, Fatma Karapinar, Marcel Bouvy, Mariëlle Emmelot, Svetlana Belitser, Benoit Boland, Denis O'Mahony, Kevin D Murphy, Moa Haller, Paola Salari, Matthias Schwenkglenks, Nicolas Rodondi, Toine Egberts, Wilma Knol

Research output: Contribution to journalArticleAcademicpeer-review

1 Downloads (Pure)

Abstract

Aim: To explore the association between medication use-related factors and quality of life in older hospitalised patients with polypharmacy. Findings: Hyperpolypharmacy, a high anticholinergic and sedative burden, presence of multiple prescribing omissions (based on START criteria), the use of opioids, antibiotics and benzodiazepines, and high medication complexity were associated with a lower quality of life. Message: Due to the association with quality of life, evaluating medication use-related factors, especially medication complexity as a novel factor, is important for hospitalised older patients with (hyper)polypharmacy.

Original languageEnglish
Pages (from-to)1713–1723
Number of pages11
JournalEuropean Geriatric Medicine
Volume15
Issue number6
Early online date20 Aug 2024
DOIs
Publication statusPublished - Dec 2024

Keywords

  • HRQoL
  • Quality of life
  • Medication use
  • Medication complexity
  • Polypharmacy

Fingerprint

Dive into the research topics of 'The association between medication use and health-related quality of life in multimorbid older patients with polypharmacy'. Together they form a unique fingerprint.

Cite this