The appearance of transferrin receptors on cultured human cytotrophoblast and in vitro-formed syncytiotrophoblast

M B Bierings, H J Adriaansen, J P Van Dijk

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Using trypsinization and Percoll gradient centrifugation, mononuclear cell populations were prepared from human term placentae. These populations consist mainly of cytotrophoblast, which probably lacks transferrin receptors. In vitro, transferrin receptors appear on these mononuclear cells and on syncytiotrophoblast formed in vitro, independently, of cellular fusion and proliferative state.

Original languageEnglish
Pages (from-to)387-96
Number of pages10
JournalPlacenta
Volume9
Issue number4
Publication statusPublished - 1 Jul 1988

Keywords

  • Antibodies, Monoclonal
  • Antigens, Surface
  • Cells, Cultured
  • Female
  • Fluorescent Antibody Technique
  • Humans
  • Placenta
  • Pregnancy
  • Receptors, Transferrin
  • Trophoblasts

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