The added value of [18 f]fdg pet/ct in the management of invasive fungal infections

Alfred O. Ankrah; Dina Creemers-Schild; Bart de Keizer; Hans C. Klein; Rudi A.J.O. Dierckx; Thomas C. Kwee; Lambert F.R. Span; Pim A. de Jong; Mike M. Sathekge; Andor W.J.M. Glaudemans

doi:10.3390/diagnostics11010137

The added value of [¹⁸ f]fdg pet/ct in the management of invasive fungal infections

Alfred O. Ankrah^*
, Dina Creemers-Schild
, Bart de Keizer
, Hans C. Klein
, Rudi A.J.O. Dierckx
, Thomas C. Kwee
, Lambert F.R. Span
, Pim A. de Jong
, Mike M. Sathekge
, Andor W.J.M. Glaudemans

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [¹⁸ F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [¹⁸ F]FDG PET/CT when added to the most frequently used anatomy-based studies in the evaluation of IFIs. The study was conducted in two University Medical Centers in the Netherlands. Reports of [¹⁸ F]FDG PET/CT and anatomy-based imaging performed within two weeks of the [¹⁸ F]FDG PET/CT scan were retrieved, and the presence and sites of IFI lesions were documented for each procedure. We included 155 [¹⁸ F]FDG PET/CT scans performed in 73 patients. A total of 216 anatomy-based studies including 80 chest X-rays, 89 computed tomography studies, 14 magnetic resonance imaging studies, and 33 ultrasound imaging studies were studied. The anatomy-based studies were concordant with the [¹⁸ F]FDG PET/CT for 94.4% of the scans performed. [¹⁸ F]FDG PET/CT detected IFI lesions outside of the areas imaged by the anatomy-based studies in 48.6% of the scans. In 74% of the patients, [¹⁸ F]FDG PET/CT added value in the management of the IFIs.

Original language	English
Article number	137
Number of pages	13
Journal	Diagnostics
Volume	11
Issue number	1
DOIs	https://doi.org/10.3390/diagnostics11010137
Publication status	Published - Jan 2021

Keywords

Chest X-ray
CT
Invasive fungal infections
MRI
PET
Ultrasound
invasive fungal infections
chest X-ray
ultrasound

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10.3390/diagnostics11010137

diagnostics-11-00137-v2Final published version, 1.6 MB

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title = "The added value of [18 f]fdg pet/ct in the management of invasive fungal infections",

abstract = "Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [18 F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [18 F]FDG PET/CT when added to the most frequently used anatomy-based studies in the evaluation of IFIs. The study was conducted in two University Medical Centers in the Netherlands. Reports of [18 F]FDG PET/CT and anatomy-based imaging performed within two weeks of the [18 F]FDG PET/CT scan were retrieved, and the presence and sites of IFI lesions were documented for each procedure. We included 155 [18 F]FDG PET/CT scans performed in 73 patients. A total of 216 anatomy-based studies including 80 chest X-rays, 89 computed tomography studies, 14 magnetic resonance imaging studies, and 33 ultrasound imaging studies were studied. The anatomy-based studies were concordant with the [18 F]FDG PET/CT for 94.4\% of the scans performed. [18 F]FDG PET/CT detected IFI lesions outside of the areas imaged by the anatomy-based studies in 48.6\% of the scans. In 74\% of the patients, [18 F]FDG PET/CT added value in the management of the IFIs.",

keywords = "Chest X-ray, CT, Invasive fungal infections, MRI, PET, Ultrasound, invasive fungal infections, chest X-ray, ultrasound",

author = "Ankrah, \{Alfred O.\} and Dina Creemers-Schild and \{de Keizer\}, Bart and Klein, \{Hans C.\} and Dierckx, \{Rudi A.J.O.\} and Kwee, \{Thomas C.\} and Span, \{Lambert F.R.\} and \{de Jong\}, \{Pim A.\} and Sathekge, \{Mike M.\} and Glaudemans, \{Andor W.J.M.\}",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Li-censee MDPI, Basel, Switzerland.",

year = "2021",

month = jan,

doi = "10.3390/diagnostics11010137",

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T1 - The added value of [18 f]fdg pet/ct in the management of invasive fungal infections

AU - Ankrah, Alfred O.

AU - Creemers-Schild, Dina

AU - de Keizer, Bart

AU - Klein, Hans C.

AU - Dierckx, Rudi A.J.O.

AU - Kwee, Thomas C.

AU - Span, Lambert F.R.

AU - de Jong, Pim A.

AU - Sathekge, Mike M.

AU - Glaudemans, Andor W.J.M.

PY - 2021/1

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N2 - Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [18 F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [18 F]FDG PET/CT when added to the most frequently used anatomy-based studies in the evaluation of IFIs. The study was conducted in two University Medical Centers in the Netherlands. Reports of [18 F]FDG PET/CT and anatomy-based imaging performed within two weeks of the [18 F]FDG PET/CT scan were retrieved, and the presence and sites of IFI lesions were documented for each procedure. We included 155 [18 F]FDG PET/CT scans performed in 73 patients. A total of 216 anatomy-based studies including 80 chest X-rays, 89 computed tomography studies, 14 magnetic resonance imaging studies, and 33 ultrasound imaging studies were studied. The anatomy-based studies were concordant with the [18 F]FDG PET/CT for 94.4% of the scans performed. [18 F]FDG PET/CT detected IFI lesions outside of the areas imaged by the anatomy-based studies in 48.6% of the scans. In 74% of the patients, [18 F]FDG PET/CT added value in the management of the IFIs.

AB - Anatomy-based imaging methods are the usual imaging methods used in assessing invasive fungal infections (IFIs). [18 F]FDG PET/CT has also been used in the evaluation of IFIs. We assessed the added value of [18 F]FDG PET/CT when added to the most frequently used anatomy-based studies in the evaluation of IFIs. The study was conducted in two University Medical Centers in the Netherlands. Reports of [18 F]FDG PET/CT and anatomy-based imaging performed within two weeks of the [18 F]FDG PET/CT scan were retrieved, and the presence and sites of IFI lesions were documented for each procedure. We included 155 [18 F]FDG PET/CT scans performed in 73 patients. A total of 216 anatomy-based studies including 80 chest X-rays, 89 computed tomography studies, 14 magnetic resonance imaging studies, and 33 ultrasound imaging studies were studied. The anatomy-based studies were concordant with the [18 F]FDG PET/CT for 94.4% of the scans performed. [18 F]FDG PET/CT detected IFI lesions outside of the areas imaged by the anatomy-based studies in 48.6% of the scans. In 74% of the patients, [18 F]FDG PET/CT added value in the management of the IFIs.

KW - Chest X-ray

KW - CT

KW - Invasive fungal infections

KW - MRI

KW - PET

KW - Ultrasound

KW - invasive fungal infections

KW - chest X-ray

KW - ultrasound

UR - https://www.scopus.com/pages/publications/85107156593

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DO - 10.3390/diagnostics11010137

M3 - Article

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AN - SCOPUS:85107156593

SN - 2075-4418

VL - 11

JO - Diagnostics

JF - Diagnostics

IS - 1

M1 - 137

ER -

The added value of [¹⁸ f]fdg pet/ct in the management of invasive fungal infections

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Keywords

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