TCR engineered T cell therapy from concepts to clinic

G.J.J. Kierkels

TCR engineered T cell therapy from concepts to clinic

G.J.J. Kierkels

Center for Translational Immunology (CTI) Research

Research output: Thesis › Doctoral thesis 1 (Research UU / Graduation UU)

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Abstract

The increased understanding of the human immune system and its ability
to detect and eradicate tumor cells has led to a promising wave of novel
therapeutics which have the potency to become the new standard of care.
This thesis aims to contribute to the development of novel cell therapy
products and the GMP manufacturing thereof.

Original language	English
Awarding Institution	University Medical Center (UMC) Utrecht
Supervisors/Advisors	Kuball, Jurgen, Primary supervisor Sebestyen, Zsolt, Co-supervisor
Award date	9 Apr 2019
Publisher	Utrecht University
Print ISBNs	978-94-6380-266-6
Publication status	Published - 9 Apr 2019

Keywords

Tumor Immunology
Cancer Immunotherapy
T cell engineering
GMP manufacturing

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title = "TCR engineered T cell therapy from concepts to clinic",

abstract = "The increased understanding of the human immune system and its ability to detect and eradicate tumor cells has led to a promising wave of novel therapeutics which have the potency to become the new standard of care. This thesis aims to contribute to the development of novel cell therapy products and the GMP manufacturing thereof.",

keywords = "Tumor Immunology, Cancer Immunotherapy, T cell engineering, GMP manufacturing",

author = "G.J.J. Kierkels",

year = "2019",

month = apr,

day = "9",

language = "English",

isbn = "978-94-6380-266-6",

publisher = "Utrecht University",

type = "Doctoral thesis 1 (Research UU / Graduation UU)",

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TY - THES

T1 - TCR engineered T cell therapy from concepts to clinic

AU - Kierkels, G.J.J.

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Y1 - 2019/4/9

N2 - The increased understanding of the human immune system and its ability to detect and eradicate tumor cells has led to a promising wave of novel therapeutics which have the potency to become the new standard of care. This thesis aims to contribute to the development of novel cell therapy products and the GMP manufacturing thereof.

AB - The increased understanding of the human immune system and its ability to detect and eradicate tumor cells has led to a promising wave of novel therapeutics which have the potency to become the new standard of care. This thesis aims to contribute to the development of novel cell therapy products and the GMP manufacturing thereof.

KW - Tumor Immunology

KW - Cancer Immunotherapy

KW - T cell engineering

KW - GMP manufacturing

M3 - Doctoral thesis 1 (Research UU / Graduation UU)

SN - 978-94-6380-266-6

PB - Utrecht University

ER -

TCR engineered T cell therapy from concepts to clinic

Abstract

Keywords

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