Target-selected mutagenesis of the rat

Bart M.G. Smits; Josine Mudde; Ronald H.A. Plasterk; Edwin Cuppen

doi:10.1016/j.ygeno.2003.08.010

Target-selected mutagenesis of the rat

Bart M.G. Smits
, Josine Mudde
, Ronald H.A. Plasterk
, Edwin Cuppen^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

65 Citations (Scopus)

Abstract

The rat is one of the most extensively studied model organisms, and with its genome being sequenced, tools to manipulate gene function in vivo have become increasingly important. We here report proof of principle for target-selected mutagenesis as a reverse genetic or knockout approach for the rat.

Original language	English
Pages (from-to)	332-334
Number of pages	3
Journal	Genomics
Volume	83
Issue number	2
DOIs	https://doi.org/10.1016/j.ygeno.2003.08.010
Publication status	Published - 1 Jan 2004

Access to Document

10.1016/j.ygeno.2003.08.010

Cite this

@article{b3289b0632174762ac2015c21d3bc6f6,

title = "Target-selected mutagenesis of the rat",

abstract = "The rat is one of the most extensively studied model organisms, and with its genome being sequenced, tools to manipulate gene function in vivo have become increasingly important. We here report proof of principle for target-selected mutagenesis as a reverse genetic or knockout approach for the rat.",

author = "Smits, \{Bart M.G.\} and Josine Mudde and Plasterk, \{Ronald H.A.\} and Edwin Cuppen",

year = "2004",

month = jan,

day = "1",

doi = "10.1016/j.ygeno.2003.08.010",

language = "English",

volume = "83",

pages = "332--334",

journal = "Genomics",

issn = "0888-7543",

publisher = "Academic Press Inc.",

number = "2",

}

TY - JOUR

T1 - Target-selected mutagenesis of the rat

AU - Smits, Bart M.G.

AU - Mudde, Josine

AU - Plasterk, Ronald H.A.

AU - Cuppen, Edwin

PY - 2004/1/1

Y1 - 2004/1/1

N2 - The rat is one of the most extensively studied model organisms, and with its genome being sequenced, tools to manipulate gene function in vivo have become increasingly important. We here report proof of principle for target-selected mutagenesis as a reverse genetic or knockout approach for the rat.

AB - The rat is one of the most extensively studied model organisms, and with its genome being sequenced, tools to manipulate gene function in vivo have become increasingly important. We here report proof of principle for target-selected mutagenesis as a reverse genetic or knockout approach for the rat.

UR - https://www.scopus.com/pages/publications/0346728736

U2 - 10.1016/j.ygeno.2003.08.010

DO - 10.1016/j.ygeno.2003.08.010

M3 - Article

C2 - 14706462

AN - SCOPUS:0346728736

SN - 0888-7543

VL - 83

SP - 332

EP - 334

JO - Genomics

JF - Genomics

IS - 2

ER -

Target-selected mutagenesis of the rat

Abstract

Access to Document

Other files and links

Fingerprint

Cite this