Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias.

F.J.T. Staal; H.C. Clevers

Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias.

Translated title of the contribution: Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias.

F.J.T. Staal
, H.C. Clevers

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.

Translated title of the contribution	Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias.
Original language	Undefined/Unknown
Pages (from-to)	761-3
Number of pages	3
Journal	Immunity
Volume	37
Issue number	5
Publication status	Published - 2012

Cite this

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title = "Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias.",

abstract = "The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.",

author = "F.J.T. Staal and H.C. Clevers",

year = "2012",

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AU - Staal, F.J.T.

AU - Clevers, H.C.

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N2 - The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.

AB - The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.

M3 - Article

SN - 1074-7613

VL - 37

SP - 761

EP - 763

JO - Immunity

JF - Immunity

IS - 5

ER -

Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias.

Abstract

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