Abstract
The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.
| Translated title of the contribution | Tales of the unexpected: tcf1 functions as a tumor suppressor for leukemias. |
|---|---|
| Original language | Undefined/Unknown |
| Pages (from-to) | 761-3 |
| Number of pages | 3 |
| Journal | Immunity |
| Volume | 37 |
| Issue number | 5 |
| Publication status | Published - 2012 |