Abstract
Objectives: We evaluated the presence and frequency of spin practices and poor reporting standards in studies that developed and/or validated clinical prediction models using supervised machine learning techniques. Study Design and Setting: We systematically searched PubMed from 01/2018 to 12/2019 to identify diagnostic and prognostic prediction model studies using supervised machine learning. No restrictions were placed on data source, outcome, or clinical specialty. Results: We included 152 studies: 38% reported diagnostic models and 62% prognostic models. When reported, discrimination was described without precision estimates in 53/71 abstracts (74.6% [95% CI 63.4–83.3]) and 53/81 main texts (65.4% [95% CI 54.6–74.9]). Of the 21 abstracts that recommended the model to be used in daily practice, 20 (95.2% [95% CI 77.3–99.8]) lacked any external validation of the developed models. Likewise, 74/133 (55.6% [95% CI 47.2–63.8]) studies made recommendations for clinical use in their main text without any external validation. Reporting guidelines were cited in 13/152 (8.6% [95% CI 5.1–14.1]) studies. Conclusion: Spin practices and poor reporting standards are also present in studies on prediction models using machine learning techniques. A tailored framework for the identification of spin will enhance the sound reporting of prediction model studies.
| Original language | English |
|---|---|
| Pages (from-to) | 99-110 |
| Number of pages | 12 |
| Journal | Journal of Clinical Epidemiology |
| Volume | 158 |
| Early online date | 4 Apr 2023 |
| DOIs | |
| Publication status | Published - Jun 2023 |
Keywords
- Development
- Diagnosis
- Misinterpretation
- Overextrapolation
- Overinterpretation
- Prognosis
- Spin
- Validation
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