Syphilis: a reversible cause of nephrotic syndrome

M Louis Handoko; Marjolijn Duijvestein; Cornelis G Scheepstra; Carola W H de Fijter

doi:10.1136/bcr-2012-008279

Syphilis: a reversible cause of nephrotic syndrome

M Louis Handoko, Marjolijn Duijvestein, Cornelis G Scheepstra, Carola W H de Fijter

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A patient in his late 30s presented with symptoms consistent with a nephrotic syndrome. Renal biopsy revealed membranous nephropathy. He also mentioned a spontaneous resolving 'rash' at his glans penis after unprotected intercourse. Therefore, he was tested for sexually transmitted diseases as a possible underlying cause of his nephrotic syndrome. Serology for syphilis was positive with high titres. After a single penicillin injection, there was fast and complete clinical recovery.

Original language	English
Journal	BMJ Case Reports
Volume	2013
DOIs	https://doi.org/10.1136/bcr-2012-008279
Publication status	Published - 8 Feb 2013
Externally published	Yes

Keywords

Adult
Glomerulonephritis, Membranous/etiology
Humans
Kidney/pathology
Male
Nephrotic Syndrome/etiology
Penicillins/therapeutic use
Syphilis/complications
Syphilis Serodiagnosis

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10.1136/bcr-2012-008279

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title = "Syphilis: a reversible cause of nephrotic syndrome",

abstract = "A patient in his late 30s presented with symptoms consistent with a nephrotic syndrome. Renal biopsy revealed membranous nephropathy. He also mentioned a spontaneous resolving 'rash' at his glans penis after unprotected intercourse. Therefore, he was tested for sexually transmitted diseases as a possible underlying cause of his nephrotic syndrome. Serology for syphilis was positive with high titres. After a single penicillin injection, there was fast and complete clinical recovery.",

keywords = "Adult, Glomerulonephritis, Membranous/etiology, Humans, Kidney/pathology, Male, Nephrotic Syndrome/etiology, Penicillins/therapeutic use, Syphilis/complications, Syphilis Serodiagnosis",

author = "Handoko, {M Louis} and Marjolijn Duijvestein and Scheepstra, {Cornelis G} and {de Fijter}, {Carola W H}",

year = "2013",

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doi = "10.1136/bcr-2012-008279",

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TY - JOUR

T1 - Syphilis

T2 - a reversible cause of nephrotic syndrome

AU - Handoko, M Louis

AU - Duijvestein, Marjolijn

AU - Scheepstra, Cornelis G

AU - de Fijter, Carola W H

PY - 2013/2/8

Y1 - 2013/2/8

N2 - A patient in his late 30s presented with symptoms consistent with a nephrotic syndrome. Renal biopsy revealed membranous nephropathy. He also mentioned a spontaneous resolving 'rash' at his glans penis after unprotected intercourse. Therefore, he was tested for sexually transmitted diseases as a possible underlying cause of his nephrotic syndrome. Serology for syphilis was positive with high titres. After a single penicillin injection, there was fast and complete clinical recovery.

AB - A patient in his late 30s presented with symptoms consistent with a nephrotic syndrome. Renal biopsy revealed membranous nephropathy. He also mentioned a spontaneous resolving 'rash' at his glans penis after unprotected intercourse. Therefore, he was tested for sexually transmitted diseases as a possible underlying cause of his nephrotic syndrome. Serology for syphilis was positive with high titres. After a single penicillin injection, there was fast and complete clinical recovery.

KW - Adult

KW - Glomerulonephritis, Membranous/etiology

KW - Humans

KW - Kidney/pathology

KW - Male

KW - Nephrotic Syndrome/etiology

KW - Penicillins/therapeutic use

KW - Syphilis/complications

KW - Syphilis Serodiagnosis

U2 - 10.1136/bcr-2012-008279

DO - 10.1136/bcr-2012-008279

M3 - Article

C2 - 23396933

SN - 1757-790X

VL - 2013

JO - BMJ Case Reports

JF - BMJ Case Reports

ER -

Syphilis: a reversible cause of nephrotic syndrome

Abstract

Keywords

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