Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

Hallie C Prescott; Massimo Antonelli; Waleed Alhazzani; Morten Hylander Møller; Fayez Alshamsi; Luciano C P Azevedo; Emilie Belley-Cote; Jan De Waele; Lennie Derde; Joanna C Dionne; Laura Evans; Hayley B Gershengorn; Carol L Hodgson; Kimia Honarmand; Jozef Kesecioglu; Lauralyn McIntyre; Mervyn Mer; Mark E Nunnally; Simon J W Oczkowski; Bram Rochwerg; Olurotimi Olaolu Akinola; Kwame A Akuamoah-Boateng; Laura Alberto; Derek C Angus; Yaseen M Arabi; Elie Azoulay; Maurizio Cecconi; Pauline F Convocar; Gennaro De Pascale; Kent Doi; Bin Du; Moritoki Egi; Marie-Carmelle Elie-Turenne; Ricard Ferrer; Alison Fox-Robichaud; Craig French; Yonathan Freund; Michelle Ng Gong; Caleb P Hale; Naomi E Hammond; Madiha Hashmi; Leo Heunks; Theodore J Iwashyna; Shevin T Jacob; Michael Klompas; Arthur Kwizera; Murdoch Leeies; Joanna D Lejnieks; Mitchell M Levy; Flavia R Machado; Marcelo O Maia; Henry Masur; Ryan C Maves; Steven McGloughlin; Joanne McPeake; Nicholas M Mohr; Sheila Nainan Myatra; Marlies Ostermann; Sandra L Peake; Mathias W Pletz; Jason A Roberts; Regis G Rosa; Robert G Sawyer; Christa A Schorr; Steven Q Simpson; Li Weng; W Joost Wiersinga; Andrew Rhodes; Craig M Coopersmith

doi:10.1097/CCM.0000000000007075

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

Hallie C Prescott^*
, Massimo Antonelli
, Waleed Alhazzani
, Morten Hylander Møller
, Fayez Alshamsi
, Luciano C P Azevedo
, Emilie Belley-Cote
, Jan De Waele
, Lennie Derde
, Joanna C Dionne
, Laura Evans
, Hayley B Gershengorn
, Carol L Hodgson
, Kimia Honarmand
, Jozef Kesecioglu
, Lauralyn McIntyre
, Mervyn Mer
, Mark E Nunnally
, Simon J W Oczkowski
, Bram Rochwerg

Olurotimi Olaolu Akinola, Kwame A Akuamoah-Boateng, Laura Alberto, Derek C Angus, Yaseen M Arabi, Elie Azoulay, Maurizio Cecconi, Pauline F Convocar, Gennaro De Pascale, Kent Doi, Bin Du, Moritoki Egi, Marie-Carmelle Elie-Turenne, Ricard Ferrer, Alison Fox-Robichaud, Craig French, Yonathan Freund, Michelle Ng Gong, Caleb P Hale, Naomi E Hammond, Madiha Hashmi, Leo Heunks, Theodore J Iwashyna, Shevin T Jacob, Michael Klompas, Arthur Kwizera, Murdoch Leeies, Joanna D Lejnieks, Mitchell M Levy, Flavia R Machado, Marcelo O Maia, Henry Masur, Ryan C Maves, Steven McGloughlin, Joanne McPeake, Nicholas M Mohr, Sheila Nainan Myatra, Marlies Ostermann, Sandra L Peake, Mathias W Pletz, Jason A Roberts, Regis G Rosa, Robert G Sawyer, Christa A Schorr, Steven Q Simpson, Li Weng, W Joost Wiersinga, Andrew Rhodes, Craig M Coopersmith

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	725-812
Number of pages	88
Journal	Critical care medicine
Volume	54
Issue number	4
Early online date	23 Mar 2026
DOIs	https://doi.org/10.1097/CCM.0000000000007075
Publication status	Published - 1 Apr 2026

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Prescott, H. C., Antonelli, M., Alhazzani, W., Møller, M. H., Alshamsi, F., Azevedo, L. C. P., Belley-Cote, E., De Waele, J., Derde, L., Dionne, J. C., Evans, L., Gershengorn, H. B., Hodgson, C. L., Honarmand, K., Kesecioglu, J., McIntyre, L., Mer, M., Nunnally, M. E., Oczkowski, S. J. W., ... Coopersmith, C. M. (2026). Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026. Critical care medicine, 54(4), 725-812. https://doi.org/10.1097/CCM.0000000000007075

@article{b0e5a5ed128c454fb224b68f1e685d0b,

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author = "Prescott, \{Hallie C\} and Massimo Antonelli and Waleed Alhazzani and M{\o}ller, \{Morten Hylander\} and Fayez Alshamsi and Azevedo, \{Luciano C P\} and Emilie Belley-Cote and \{De Waele\}, Jan and Lennie Derde and Dionne, \{Joanna C\} and Laura Evans and Gershengorn, \{Hayley B\} and Hodgson, \{Carol L\} and Kimia Honarmand and Jozef Kesecioglu and Lauralyn McIntyre and Mervyn Mer and Nunnally, \{Mark E\} and Oczkowski, \{Simon J W\} and Bram Rochwerg and Akinola, \{Olurotimi Olaolu\} and Akuamoah-Boateng, \{Kwame A\} and Laura Alberto and Angus, \{Derek C\} and Arabi, \{Yaseen M\} and Elie Azoulay and Maurizio Cecconi and Convocar, \{Pauline F\} and \{De Pascale\}, Gennaro and Kent Doi and Bin Du and Moritoki Egi and Marie-Carmelle Elie-Turenne and Ricard Ferrer and Alison Fox-Robichaud and Craig French and Yonathan Freund and Gong, \{Michelle Ng\} and Hale, \{Caleb P\} and Hammond, \{Naomi E\} and Madiha Hashmi and Leo Heunks and Iwashyna, \{Theodore J\} and Jacob, \{Shevin T\} and Michael Klompas and Arthur Kwizera and Murdoch Leeies and Lejnieks, \{Joanna D\} and Levy, \{Mitchell M\} and Machado, \{Flavia R\} and Maia, \{Marcelo O\} and Henry Masur and Maves, \{Ryan C\} and Steven McGloughlin and Joanne McPeake and Mohr, \{Nicholas M\} and Myatra, \{Sheila Nainan\} and Marlies Ostermann and Peake, \{Sandra L\} and Pletz, \{Mathias W\} and Roberts, \{Jason A\} and Rosa, \{Regis G\} and Sawyer, \{Robert G\} and Schorr, \{Christa A\} and Simpson, \{Steven Q\} and Li Weng and Wiersinga, \{W Joost\} and Andrew Rhodes and Coopersmith, \{Craig M\}",

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doi = "10.1097/CCM.0000000000007075",

language = "English",

volume = "54",

pages = "725--812",

journal = "Critical care medicine",

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Prescott, HC, Antonelli, M, Alhazzani, W, Møller, MH, Alshamsi, F, Azevedo, LCP, Belley-Cote, E, De Waele, J, Derde, L, Dionne, JC, Evans, L, Gershengorn, HB, Hodgson, CL, Honarmand, K, Kesecioglu, J, McIntyre, L, Mer, M, Nunnally, ME, Oczkowski, SJW, Rochwerg, B, Akinola, OO, Akuamoah-Boateng, KA, Alberto, L, Angus, DC, Arabi, YM, Azoulay, E, Cecconi, M, Convocar, PF, De Pascale, G, Doi, K, Du, B, Egi, M, Elie-Turenne, M-C, Ferrer, R, Fox-Robichaud, A, French, C, Freund, Y, Gong, MN, Hale, CP, Hammond, NE, Hashmi, M, Heunks, L, Iwashyna, TJ, Jacob, ST, Klompas, M, Kwizera, A, Leeies, M, Lejnieks, JD, Levy, MM, Machado, FR, Maia, MO, Masur, H, Maves, RC, McGloughlin, S, McPeake, J, Mohr, NM, Myatra, SN, Ostermann, M, Peake, SL, Pletz, MW, Roberts, JA, Rosa, RG, Sawyer, RG, Schorr, CA, Simpson, SQ, Weng, L, Wiersinga, WJ, Rhodes, A & Coopersmith, CM 2026, 'Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026', Critical care medicine, vol. 54, no. 4, pp. 725-812. https://doi.org/10.1097/CCM.0000000000007075

TY - JOUR

T1 - Surviving Sepsis Campaign

T2 - International Guidelines for Management of Sepsis and Septic Shock 2026

AU - Prescott, Hallie C

AU - Antonelli, Massimo

AU - Alhazzani, Waleed

AU - Møller, Morten Hylander

AU - Alshamsi, Fayez

AU - Azevedo, Luciano C P

AU - Belley-Cote, Emilie

AU - De Waele, Jan

AU - Derde, Lennie

AU - Dionne, Joanna C

AU - Evans, Laura

AU - Gershengorn, Hayley B

AU - Hodgson, Carol L

AU - Honarmand, Kimia

AU - Kesecioglu, Jozef

AU - McIntyre, Lauralyn

AU - Mer, Mervyn

AU - Nunnally, Mark E

AU - Oczkowski, Simon J W

AU - Rochwerg, Bram

AU - Akinola, Olurotimi Olaolu

AU - Akuamoah-Boateng, Kwame A

AU - Alberto, Laura

AU - Angus, Derek C

AU - Arabi, Yaseen M

AU - Azoulay, Elie

AU - Cecconi, Maurizio

AU - Convocar, Pauline F

AU - De Pascale, Gennaro

AU - Doi, Kent

AU - Du, Bin

AU - Egi, Moritoki

AU - Elie-Turenne, Marie-Carmelle

AU - Ferrer, Ricard

AU - Fox-Robichaud, Alison

AU - French, Craig

AU - Freund, Yonathan

AU - Gong, Michelle Ng

AU - Hale, Caleb P

AU - Hammond, Naomi E

AU - Hashmi, Madiha

AU - Heunks, Leo

AU - Iwashyna, Theodore J

AU - Jacob, Shevin T

AU - Klompas, Michael

AU - Kwizera, Arthur

AU - Leeies, Murdoch

AU - Lejnieks, Joanna D

AU - Levy, Mitchell M

AU - Machado, Flavia R

AU - Maia, Marcelo O

AU - Masur, Henry

AU - Maves, Ryan C

AU - McGloughlin, Steven

AU - McPeake, Joanne

AU - Mohr, Nicholas M

AU - Myatra, Sheila Nainan

AU - Ostermann, Marlies

AU - Peake, Sandra L

AU - Pletz, Mathias W

AU - Roberts, Jason A

AU - Rosa, Regis G

AU - Sawyer, Robert G

AU - Schorr, Christa A

AU - Simpson, Steven Q

AU - Weng, Li

AU - Wiersinga, W Joost

AU - Rhodes, Andrew

AU - Coopersmith, Craig M

PY - 2026/4/1

Y1 - 2026/4/1

UR - https://www.scopus.com/pages/publications/105034180957

U2 - 10.1097/CCM.0000000000007075

DO - 10.1097/CCM.0000000000007075

M3 - Article

C2 - 41869847

SN - 0090-3493

VL - 54

SP - 725

EP - 812

JO - Critical care medicine

JF - Critical care medicine

IS - 4

ER -

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

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