Surgical Accuracy of 3-Tesla Versus 7-Tesla Magnetic Resonance Imaging in Deep Brain Stimulation for Parkinson Disease

Peter Jan van Laar; D L Marinus Oterdoom; Gert J Ter Horst; Arjen L J van Hulzen; Eva K L de Graaf; Hans Hoogduin; Linda C Meiners; J Marc C van Dijk

doi:10.1016/j.wneu.2016.06.084

Surgical Accuracy of 3-Tesla Versus 7-Tesla Magnetic Resonance Imaging in Deep Brain Stimulation for Parkinson Disease

Peter Jan van Laar
, D L Marinus Oterdoom
, Gert J Ter Horst
, Arjen L J van Hulzen
, Eva K L de Graaf
, Hans Hoogduin
, Linda C Meiners
, J Marc C van Dijk

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

BACKGROUND: In deep brain stimulation (DBS), accurate placement of the lead is critical. Target definition is highly dependent on visual recognition on magnetic resonance imaging (MRI). We prospectively investigated whether the 7-T MRI enabled better visualization of targets and led to better placement of leads compared with the 1.5-T and the 3-T MRI.

METHODS: Three patients with PD (mean, 55 years) were scanned on 1.5-, 3-, and 7-T MRI before surgery. Tissue contrast and signal-to-noise ratio were measured. Target coordinates were noted on MRI and during surgery. Differences were analyzed with post-hoc analysis of variance.

RESULTS: The 7-T MRI demonstrated a significant improvement in tissue visualization (P < 0.005) and signal-to-noise ratio (P < 0.005). However, no difference in the target coordinates was found between the 7-T and the 3-T MRI.

CONCLUSIONS: Although the 7-T MRI enables a significant better visualization of the DBS target in patients with PD, we found no clinical benefit for the placement of the DBS leads.

Original language	English
Pages (from-to)	410-412
Number of pages	3
Journal	World Neurosurgery
Volume	93
DOIs	https://doi.org/10.1016/j.wneu.2016.06.084
Publication status	Published - Sept 2016

Keywords

7-Tesla MRI; Accuracy; Deep brain stimulation; Parkinson disease

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10.1016/j.wneu.2016.06.084

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@article{11530e4022f34f629a135c72f4f4cee6,

title = "Surgical Accuracy of 3-Tesla Versus 7-Tesla Magnetic Resonance Imaging in Deep Brain Stimulation for Parkinson Disease",

abstract = "BACKGROUND: In deep brain stimulation (DBS), accurate placement of the lead is critical. Target definition is highly dependent on visual recognition on magnetic resonance imaging (MRI). We prospectively investigated whether the 7-T MRI enabled better visualization of targets and led to better placement of leads compared with the 1.5-T and the 3-T MRI.METHODS: Three patients with PD (mean, 55 years) were scanned on 1.5-, 3-, and 7-T MRI before surgery. Tissue contrast and signal-to-noise ratio were measured. Target coordinates were noted on MRI and during surgery. Differences were analyzed with post-hoc analysis of variance.RESULTS: The 7-T MRI demonstrated a significant improvement in tissue visualization (P < 0.005) and signal-to-noise ratio (P < 0.005). However, no difference in the target coordinates was found between the 7-T and the 3-T MRI.CONCLUSIONS: Although the 7-T MRI enables a significant better visualization of the DBS target in patients with PD, we found no clinical benefit for the placement of the DBS leads.",

keywords = "7-Tesla MRI; Accuracy; Deep brain stimulation; Parkinson disease",

author = "\{van Laar\}, \{Peter Jan\} and Oterdoom, \{D L Marinus\} and \{Ter Horst\}, \{Gert J\} and \{van Hulzen\}, \{Arjen L J\} and \{de Graaf\}, \{Eva K L\} and Hans Hoogduin and Meiners, \{Linda C\} and \{van Dijk\}, \{J Marc C\}",

year = "2016",

month = sep,

doi = "10.1016/j.wneu.2016.06.084",

language = "English",

volume = "93",

pages = "410--412",

journal = "World Neurosurgery",

issn = "1878-8750",

publisher = "Elsevier",

}

TY - JOUR

T1 - Surgical Accuracy of 3-Tesla Versus 7-Tesla Magnetic Resonance Imaging in Deep Brain Stimulation for Parkinson Disease

AU - van Laar, Peter Jan

AU - Oterdoom, D L Marinus

AU - Ter Horst, Gert J

AU - van Hulzen, Arjen L J

AU - de Graaf, Eva K L

AU - Hoogduin, Hans

AU - Meiners, Linda C

AU - van Dijk, J Marc C

PY - 2016/9

Y1 - 2016/9

N2 - BACKGROUND: In deep brain stimulation (DBS), accurate placement of the lead is critical. Target definition is highly dependent on visual recognition on magnetic resonance imaging (MRI). We prospectively investigated whether the 7-T MRI enabled better visualization of targets and led to better placement of leads compared with the 1.5-T and the 3-T MRI.METHODS: Three patients with PD (mean, 55 years) were scanned on 1.5-, 3-, and 7-T MRI before surgery. Tissue contrast and signal-to-noise ratio were measured. Target coordinates were noted on MRI and during surgery. Differences were analyzed with post-hoc analysis of variance.RESULTS: The 7-T MRI demonstrated a significant improvement in tissue visualization (P < 0.005) and signal-to-noise ratio (P < 0.005). However, no difference in the target coordinates was found between the 7-T and the 3-T MRI.CONCLUSIONS: Although the 7-T MRI enables a significant better visualization of the DBS target in patients with PD, we found no clinical benefit for the placement of the DBS leads.

AB - BACKGROUND: In deep brain stimulation (DBS), accurate placement of the lead is critical. Target definition is highly dependent on visual recognition on magnetic resonance imaging (MRI). We prospectively investigated whether the 7-T MRI enabled better visualization of targets and led to better placement of leads compared with the 1.5-T and the 3-T MRI.METHODS: Three patients with PD (mean, 55 years) were scanned on 1.5-, 3-, and 7-T MRI before surgery. Tissue contrast and signal-to-noise ratio were measured. Target coordinates were noted on MRI and during surgery. Differences were analyzed with post-hoc analysis of variance.RESULTS: The 7-T MRI demonstrated a significant improvement in tissue visualization (P < 0.005) and signal-to-noise ratio (P < 0.005). However, no difference in the target coordinates was found between the 7-T and the 3-T MRI.CONCLUSIONS: Although the 7-T MRI enables a significant better visualization of the DBS target in patients with PD, we found no clinical benefit for the placement of the DBS leads.

KW - 7-Tesla MRI; Accuracy; Deep brain stimulation; Parkinson disease

U2 - 10.1016/j.wneu.2016.06.084

DO - 10.1016/j.wneu.2016.06.084

M3 - Article

C2 - 27368505

SN - 1878-8750

VL - 93

SP - 410

EP - 412

JO - World Neurosurgery

JF - World Neurosurgery

ER -

Surgical Accuracy of 3-Tesla Versus 7-Tesla Magnetic Resonance Imaging in Deep Brain Stimulation for Parkinson Disease

Abstract

Keywords

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