Superior effect of arthroscopic lavage compared with needle aspiration in the treatment of inflammatory arthritis of the knee

M van Oosterhout, J K Sont, J M van Laar

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVES: To compare the duration of symptom relief after arthroscopic lavage versus needle aspiration in gonarthritis.

METHODS: A retrospective chart analysis was performed in 50 patients with non-septic inflammatory arthritis of the knee who underwent arthroscopic lavage because of relapsing or persisting arthritis after needle aspiration. The primary outcome measure was the time until symptomatic recurrence of knee synovitis.

RESULTS: Needle aspiration was associated with a 3.0 times greater risk of recurrence of arthritis compared with arthroscopic lavage within 12 months (P<0.001, 95% confidence interval 2.1-4.4). Patients with longer disease duration and who had used more disease-modifying anti-rheumatic drugs (DMARDs) had a significantly lower risk of recurrence of arthritis compared with patients with shorter disease duration and a lower number of previous DMARDs (P=0.04 and 0.02 respectively). Corticosteroids augmented the effect of both interventions.

CONCLUSIONS: Our results indicate that arthroscopic lavage is an effective therapeutic modality in the treatment of inflammatory arthritis of the knee refractory to joint aspiration, especially in patients with longstanding disease.

Original languageEnglish
Pages (from-to)102-7
Number of pages6
JournalRheumatology (Oxford, England)
Volume42
Issue number1
Publication statusPublished - Jan 2003
Externally publishedYes

Keywords

  • Administration, Topical
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Inflammatory Agents
  • Antirheumatic Agents
  • Arthritis
  • Arthroscopy
  • Biopsy, Needle
  • Female
  • Follow-Up Studies
  • Glucocorticoids
  • Humans
  • Injections, Intra-Articular
  • Knee Joint
  • Male
  • Middle Aged
  • Proportional Hazards Models
  • Recurrence
  • Retrospective Studies
  • Risk
  • Synovial Fluid
  • Therapeutic Irrigation
  • Comparative Study
  • Journal Article

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