68Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma

Bart de Keizer; Gerard C. Krijger; Tessa Ververs; Robert J.J. van Es; Remco de Bree; Stefan Willems

doi:10.1007/s13139-016-0445-6

⁶⁸Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma

Bart de Keizer^*, Gerard C. Krijger, Tessa Ververs, Robert J.J. van Es, Remco de Bree, Stefan Willems

^*Corresponding author for this work

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Abstract

A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a ⁶⁸Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone metastasis was performed and pathology showed adenoid cystic carcinoma instead of prostate cancer. Immunohistochemical PSMA staining of the primary tumour showed intense PSMA expression in adenoid cystic carcinoma tumour cells. Because of the high PSMA expression of adenoid cystic carcinoma, ⁶⁸Ga-PSMA PET-CT might be a promising imaging modality for this malignancy.

Original language	English
Pages (from-to)	360-361
Number of pages	2
Journal	Nuclear Medicine and Molecular Imaging
Volume	51
Issue number	4
DOIs	https://doi.org/10.1007/s13139-016-0445-6
Publication status	Published - 1 Dec 2017

Keywords

(68)Ga-PSMA
Adenoid Cystic
Carcinoma
Immunohistochemistry
PET-CT

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title = "68Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma",

abstract = "A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a 68Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone metastasis was performed and pathology showed adenoid cystic carcinoma instead of prostate cancer. Immunohistochemical PSMA staining of the primary tumour showed intense PSMA expression in adenoid cystic carcinoma tumour cells. Because of the high PSMA expression of adenoid cystic carcinoma, 68Ga-PSMA PET-CT might be a promising imaging modality for this malignancy.",

keywords = "(68)Ga-PSMA, Adenoid Cystic, Carcinoma, Immunohistochemistry, PET-CT",

author = "{de Keizer}, Bart and Krijger, {Gerard C.} and Tessa Ververs and {van Es}, {Robert J.J.} and {de Bree}, Remco and Stefan Willems",

year = "2017",

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day = "1",

doi = "10.1007/s13139-016-0445-6",

language = "English",

volume = "51",

pages = "360--361",

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TY - JOUR

T1 - 68Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma

AU - de Keizer, Bart

AU - Krijger, Gerard C.

AU - Ververs, Tessa

AU - van Es, Robert J.J.

AU - de Bree, Remco

AU - Willems, Stefan

PY - 2017/12/1

Y1 - 2017/12/1

N2 - A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a 68Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone metastasis was performed and pathology showed adenoid cystic carcinoma instead of prostate cancer. Immunohistochemical PSMA staining of the primary tumour showed intense PSMA expression in adenoid cystic carcinoma tumour cells. Because of the high PSMA expression of adenoid cystic carcinoma, 68Ga-PSMA PET-CT might be a promising imaging modality for this malignancy.

AB - A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a 68Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone metastasis was performed and pathology showed adenoid cystic carcinoma instead of prostate cancer. Immunohistochemical PSMA staining of the primary tumour showed intense PSMA expression in adenoid cystic carcinoma tumour cells. Because of the high PSMA expression of adenoid cystic carcinoma, 68Ga-PSMA PET-CT might be a promising imaging modality for this malignancy.

KW - (68)Ga-PSMA

KW - Adenoid Cystic

KW - Carcinoma

KW - Immunohistochemistry

KW - PET-CT

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U2 - 10.1007/s13139-016-0445-6

DO - 10.1007/s13139-016-0445-6

M3 - Article

AN - SCOPUS:85037631188

SN - 1869-3474

VL - 51

SP - 360

EP - 361

JO - Nuclear Medicine and Molecular Imaging

JF - Nuclear Medicine and Molecular Imaging

IS - 4

ER -

⁶⁸Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma

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